Results 121 to 130 of about 12,941 (217)
Migraine-induced cochlear injury triggers ZBP1-mediated PANoptosis via CGRP signaling. [PDF]
Xu W +13 more
europepmc +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley +1 more source
ABSTRACT Background Presbycusis, an age‐related hearing disorder, affects communication, psychosocial functioning, and quality of life. Because its management requires long‐term engagement with rehabilitation and medication routines, psychological factors such as personality traits and coping styles may influence treatment adherence.
Zahra Davari +5 more
wiley +1 more source
Laboratory studies show KS has electroconductive properties with the ability to trap and transport protons in neurotransductive processes (Grotthuss proton shuttling). This maintains electrochemical gradients and fluxes at the neuronal cell surface in neural activation. Such processes are central to neuronal cell signaling and communication.
James Melrose
wiley +1 more source
Balance Disorders in Young and Middle‐Aged Adults: NHANES, 2001–2004 and 2021–2023
This study presents nationally‐representative estimates from two health exam surveys, NHANES 2001–2004 and 2021–2023. In the two decades between test periods, scores on the modified Romberg screening test for balance function demonstrated significantly better age‐specific performance in 2021–2023.
Howard J. Hoffman +8 more
wiley +1 more source
Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance
In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi +7 more
wiley +1 more source
Current Technical Skills Assessment Tools in Otolaryngology Residency: A Scoping Review
This systematic review of 146 studies encompassing over 3000 otolaryngology trainees identified and synthesized technical skills assessment tools across six subspecialties. Common validated frameworks included Objective Structured Assessment of Technical Skills, Task‐Specific Checklists, and Global Rating Scales, which demonstrated strong construct ...
Vanessa Helou +6 more
wiley +1 more source
3D‐Printed Electroanatomic Twins of Cadaveric Cochleae: A Platform for Cochlear Implant Testing
ABSTRACT Objectives Cochlear implants (CIs) can restore hearing to individuals with severe deafness, yet clinical outcomes vary widely because it remains difficult to predict how electrical currents interact with the unique anatomy of each cochlea. A central challenge in auditory rehabilitation is the lack of experimental systems that capture both the ...
Chloe Swords +7 more
wiley +1 more source
Does minor head injury cause cochlear concussion?
Does minor head injury has any effect on the human cochlea? 50 patients under 30 years of age admitted to hospital with head injury had a detailed history of head trauma, ENT examination and full audiological investigations on admission and six weeks later.
openaire +1 more source

