Results 191 to 200 of about 25,857 (229)
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Protective Effects of Corticosteroids and Neurosteroids on Cochlear injury
Medicinal Chemistry, 2011Dysfunction of the cochlea causes sensorineural hearing loss. Glucocorticoids have been clinically applied for sensorineural hearing loss of sudden onset, including idiopathic sudden sensorineural hearing loss, acoustic injury, Meniere's disease, and immune-mediated hearing loss.
Keiji, Tabuchi +5 more
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Calcium concentration in cochlear endolymph after vestibular labyrinth injury
NeuroReport, 2010The endolymphatic calcium concentration [Ca2+] is essential for acoustic transduction. This study investigated the changes in cochlear function caused by vestibular labyrinth destruction in the acute phase by measurement of the endocochlear potential and endolymphatic [Ca2+].Hartley guinea pigs underwent lateral semicircular canal transection with ...
Ryoukichi, Ikeda +4 more
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Cochlear Implantation After Traumatic Brain Injury
Otolaryngology–Head and Neck SurgeryAbstractObjectiveThe objective of this study is to determine if a history of traumatic brain injury (TBI) degrades postoperative the audiological performance of patients with cochlear implantation (CI).Study DesignRetrospective review.SettingDepartment of Defense‐wide database.MethodsInternational Classification of Diseases, Ninth Revision (ICD‐9) and ...
Russell W. De Jong +4 more
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Hearing Research, 2014
The dynamics of cochlear excitotoxicity can be monitored from effects on the contralateral ear. After unilateral mechanical ablation of the cochlea (in a mouse model) we observed immediate elevations in auditory brainstem evoked response (ABR) thresholds in the contralateral ear.
Jaina, Negandhi +3 more
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The dynamics of cochlear excitotoxicity can be monitored from effects on the contralateral ear. After unilateral mechanical ablation of the cochlea (in a mouse model) we observed immediate elevations in auditory brainstem evoked response (ABR) thresholds in the contralateral ear.
Jaina, Negandhi +3 more
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Inhibition of Post‐Meningitic Cochlear Injury with Cerebrospinal Fluid Irrigation
Otolaryngology–Head and Neck Surgery, 2006OBJECTIVELabyrinthitis ossificans, the pathologic ossification of the otic capsule associated with profound deafness and loss of vestibular function occurs frequently as a sequella of bacterial meningitis and subsequent purulent labyrinthitis. Experimentally, in Streptococcus pneumoniae meningitis, it has been shown that a vigorous inflammatory ...
A H, Yeung, S P, Tinling, H A, Brodie
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The Potential Risk of Carotid Injury in Cochlear Implant Surgery
The Laryngoscope, 2002AbstractBackground The advent of cochlear implantation has revolutionized the options afforded to the deaf population. With the increase in the prevalence of this procedure have come larger experiences in the associated technical challenges and complications.Results We present the evaluation and management of a patient with an unusual complication of ...
B R, Gastman +4 more
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Chronic cochlear de-efferentation and susceptibility to permanent acoustic injury
Hearing Research, 1995The question of whether olivocochlear (OC) efferent feedback can decrease permanent damage from acoustic overexposure was investigated by comparing the chronic threshold shifts and cochlear histopathology in guinea pigs either surgically de-efferented or sham-operated and then exposed (awake and unrestrained) to a 109- or 112-dB narrow-band noise ...
M C, Liberman, W Y, Gao
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Cochlear injuries induced by the combined exposure to noise and styrene
Hearing Research, 2009Workers exposed to industrial solvents are also frequently exposed to mechanical noise. In this study, a combination of a continuous noise (100 dB SPL) and an impact noise (110 dB SPL) was used to mimic the noise exposure in the workplace. A noise band of 10-20 kHz was used to induce a cochlear injury in the same cochlear region in the rat as styrene ...
Guang-Di, Chen, Donald, Henderson
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Cochlear nerve injuries caused by cerebellopontine angle manipulations
Journal of Neurosurgery, 1987✓ Changes in the response from the cochlear nerve in dogs resulting from cerebellopontine angle (CPA) manipulations were correlated with histological changes in the nerve. The aim of this study was to determine the mechanisms underlying hearing deficits incurred as a result of manipulations in the CPA.
T, Sekiya, A R, Møller
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Cochlear injury from tobramycin and other aminoglycosides in guinea pigs
The Journal of the Acoustical Society of America, 1976Cochlear toxicity of tobramycin was compared with that of four other aminoglycosidic anitbiotics. Small groups of guinea pigs received tobramycin (TM), gentamicin (GM), neomycin (NM), or kanamycin (KM) in doses of 50 and 100 mg/kg/day subcutaneously for 1–6 weeks; others received KM 200 and 400 mg/kg/day, or dihydrostreptomycin (DHSM) 400 mg/kg/day ...
J. E. Hawkins +2 more
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