Results 131 to 140 of about 398,151 (282)

A Recurrent Tympanicum Paraganglioma With a SDHD Pathogenic Variant: Fourth Reported Case

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The aim of this study is to describe a clinical case of a SDHD germline mutation associated tympanic paraganglioma (TPGL). Patients A female patient seen in the otology clinic at a tertiary care center with a diagnosis of tympanic paraganglioma and significant family history of head and neck paragangliomas.
Alex Z. Graboyes, Kevin Wong, Yonghong Huan, Jason A. Brant   +3 more
wiley   +1 more source

Anatomical Characteristics of the Facial Nerve in Patients With Cochlear Hypoplasia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To quantitatively characterize the spatial relationships between intratemporal facial nerve segments and key cochlear implantation (CI) landmarks in cochlear hypoplasia (CH), and to compare these features with age‐matched CI recipients with normal inner ear anatomy, thereby informing preoperative planning and facial nerve ...
Shu‐Jin Xue, Xing‐Mei Wei, Biao Chen, Ying Kong, Yong‐Xin Li   +4 more
wiley   +1 more source

Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Otolith is a critical component of the peripheral vestibular system responsible for detecting linear acceleration. Dysfunction of the otolith organs can lead to vertigo, balance disturbances, and gaze instability. By elucidating the physiological foundations and evaluating both current and emerging methods for assessing otolith ...
Shun Zhou, E Tian, Hua‐Jing Yang, Jun Wang, Zhao‐Qi Guo, Jing‐Yu Chen, Wan‐Di Xu, Jia‐Qi Guo, Zhang‐Hong Zhou, Shi‐Yu Shi, Xi‐Xi Yu, Xin‐Bo Gao, Ni Zhai, Xin Ma, Qing Zhang, Yi‐Sheng Lu, Su‐Lin Zhang   +16 more
wiley   +1 more source

Decoding Dual Regulatory Layers: Integrating Differential Expression and Alternative Splicing Dynamics in the Evolution of Laryngeal Echolocation Across Chiropteran Lineages

Integrative Zoology, EarlyView.
We integrated short‐read and long‐read RNA‐seq data from cochlear tissues of echolocating and non‐echolocating bats to disentangle transcriptional and post‐transcriptional regulation. Echolocating bats showed neural‐function enrichment among differentially expressed genes, while alternatively spliced genes were linked to epigenetic regulation. Overlaps
Jianyu Wu, Daoyuan Hu, Min Chen, Xiuguang Mao   +3 more
wiley   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Psychiatric and Neurodevelopmental Outcomes in Swedish Children With Hearing Loss due to Congenital Cytomegalovirus Infection: A Cross‐Sectional Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To investigate parent‐reported psychiatric, neurodevelopmental and adaptive functioning outcomes in children with congenital cytomegalovirus (cCMV)‐related sensorineural hearing loss. Methods Parents of children aged 5–12 years were recruited nationwide in Sweden into three groups: children with congenital cytomegalovirus‐related ...
A. Michel Sandström, E. Karltorp, U. Löfkvist   +2 more
wiley   +1 more source

Significance of Systemic Immune‐Inflammation and Inflammatory Response Indices in Vestibular Neuritis

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction This study investigated the relationship between vestibular neuritis and various systemic inflammatory indices—namely, neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), monocyte‐to‐lymphocyte ratio (MLR), systemic immune‐inflammation index (SII), and systemic inflammation response index (SIRI) and the ...
Tuğba Tulacı, Mustafa Utku Akbaş, Hasan Çanakçı, Tarık Yetişir, Kamil Gökçe Tulacı, Haşmet Yazıcı, Gulendam Kayıkçı, Omer Hizli   +7 more
wiley   +1 more source

The perception and production of stress and intonation by children with cochlear implants [PDF]

, 2010
Users of current cochlear implants have limited access to pitch information and hence to intonation in speech. This seems likely to have an important impact on prosodic perception.
O'Halpin, R.
core  

Modifiable Risk Factors and Hearing Loss: The National Health and Nutrition Examination Survey 1999–2020

Clinical Otolaryngology, EarlyView.
ABSTRACT Objective To explore the associations between major modifiable risk factors and hearing loss. Methods This serial cross‐sectional study was conducted within the National Health and Nutrition Examination Survey 1999–2020 in the United States. Associations were assessed using modified Poisson regression and within‐sample population attributable ...
Yulu Zheng, Tingting Li, Zhiyuan Wu, Yahong Zhu, Zheng Guo, Xingang Li   +5 more
wiley   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source