Results 61 to 70 of about 24,019 (275)

Classification and Current Management of Inner Ear Malformations

open access: yesBalkan Medical Journal, 2017
Morphologically congenital sensorineural hearing loss can be investigated under two categories. Majority of the congenital hearing loss (80%) are membranous malformations. Here the pathology involves inner ear hair cells.
Levent Sennaroğlu, Münir Demir Bajin
doaj   +1 more source

Addition of exogenous NAD+ prevents mefloquine-induced neuroaxonal and hair cell degeneration through reduction of caspase-3-mediated apoptosis in cochlear organotypic cultures. [PDF]

open access: yesPLoS ONE, 2013
Mefloquine is widely used for the treatment of malaria. However, this drug is known to induce neurological side effects including depression, anxiety, balance disorder, and sensorineural hearing loss.
Dalian Ding   +11 more
doaj   +1 more source

Somatosensory tinnitus: current evidence and future perspectives [PDF]

open access: yes, 2017
In some individuals, tinnitus can be modulated by specific maneuvers of the temporomandibular joint, head and neck, eyes, and limbs. Neuroplasticity seems to play a central role in this capacity for modulation, suggesting that abnormal interactions ...
ALTISSIMI, Giancarlo   +5 more
core   +1 more source

The Therapeutic Dilemma of Cochlear Nerve Deficiency: Cochlear or Brainstem Implantation?

open access: yesOtolaryngology–Head and Neck Surgery, 2014
ObjectiveTo compare the outcomes between 2 age‐matched cohorts of children with cochlear nerve deficiency: those receiving auditory brainstem implants (group A) or cochlear implants (group B).Study DesignRetrospective cohort study.SettingTertiary referral center.Subjects and MethodsSubjects were selected from a pool of 537 children fitted with cochlear
L. Colletti   +3 more
openaire   +5 more sources

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

open access: yesAdvanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang   +15 more
wiley   +1 more source

Bioprinted Organoids: An Innovative Engine in Biomedicine

open access: yesAdvanced Science, EarlyView.
Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and
Zhengwei Li   +11 more
wiley   +1 more source

Challenges and Opportunities in Combining Ultrasound and Inductive Coupling for Energy Supply and Bidirectional Data Exchange in Bioelectronics Medicine Implant Networks

open access: yesAdvanced Intelligent Systems, EarlyView.
In this contribution, it is shown that miniaturized nerve stimulation implants can be used in collaborative networks. Inductive links and ultrasound are combined to supply these implants with energy and data; the advantages and disadvantages of each method, as well as safety risks and possibilities for improvement are discussed and the best ...
Benedikt Szabo   +5 more
wiley   +1 more source

Development of a feline model for preclinical research of a new translabyrinthine auditory nerve implant

open access: yesFrontiers in Neuroscience
Cochlear implants are among the most successful neural prosthetic devices to date but exhibit poor frequency selectivity and the inability to consistently activate apical (low frequency) spiral ganglion neurons. These issues can limit hearing performance
W. Mitchel Thomas   +12 more
doaj   +1 more source

Y-27632, a ROCK inhibitor, improved laser-induced shock wave (LISW)-induced cochlear synaptopathy in mice

open access: yesMolecular Brain, 2021
Recently, a pathological condition called cochlear synaptopathy has been clarified, and as a disorder of the auditory nerve synapses that occurs prior to failure of hair cells, it has been recognized as a major cause of sensorineural hearing loss ...
Yutaka Koizumi   +5 more
doaj   +1 more source

Towards an Implantable Vestibular Prosthesis: The Surgical Challenges [PDF]

open access: yes, 2007
Published ...
Constandinou, T G   +3 more
core   +1 more source

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