Results 201 to 210 of about 16,526 (214)
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Cocrystal formulations: A case study of topical formulations consisting of ferulic acid cocrystals

European Journal of Pharmaceutics and Biopharmaceutics, 2020
Renaissance of cocrystals as alternative solid forms for fine-tuning physicochemical properties of active pharmaceutical ingredients (APIs) has paved way for development of marketable cocrystals. The current literature reveals established strategies for the design, synthesis and characterization of cocrystals.
Srinivasulu, Aitipamula, Surajit, Das
openaire   +2 more sources

A new cocrystal of isoniazid-quercetin with hepatoprotective effect: The design, structure, and in vitro/in vivo performance evaluation.

European Journal of Pharmaceutical Sciences, 2020
With the purpose of overcoming the serious hepatotoxicity of antituberculosis drug isoniazid (INH), a cocrystallization strategy based on complementary advantages was implemented by choosing the hepatoprotective nutraceutical quercetin (QCT) as the ...
Fang Liu   +5 more
semanticscholar   +1 more source

Chrysin cocrystals: Characterization and evaluation

Journal of Pharmaceutical and Biomedical Analysis, 2017
Solvent free mechanochemical approach is utilized to synthesise new cocrystals of chrysin using supramolecular chemistry based upon reliable synthons. Chrysin, a flavone nutraceutical with wide range of beneficial effects has critically low bioavailability on account of its poor aqueous solubility and consequently poor absorption from the ...
Renu, Chadha   +4 more
openaire   +2 more sources

Furosemide Cocrystals with Pyridines: An Interesting Case of Color Cocrystal Polymorphism

Crystal Growth & Design, 2015
Furosemide (FS), a loop diuretic drug commonly used for the treatment of hypertension and edema, exhibited color cocrystal polymorphism with coformer 4,4′-bipyridine (4BPY) in the stoichiometry 2:1, albeit both the API and the cocrystal former are colorless.
Ekta Sangtani   +6 more
openaire   +1 more source

Polymorphs, Hydrates, Cocrystals, and Cocrystal Hydrates: Thermodynamic Modeling of Theophylline Systems

Crystal Growth & Design, 2016
Polymorphic transitions and hydrate formation often occur in systems of cocrystal-forming components. To increase the efficiency of cocrystal formation and purification processes, the complex phase behavior of such systems was modeled using perturbed-chain statistical associating fluid theory (PC-SAFT).
Linda Lange, Gabriele Sadowski
openaire   +1 more source

A Novel Drug-Drug Cocrystal of Levofloxacin and Metacetamol: Reduced Hygroscopicity and Improved Photostability of Levofloxacin.

Journal of Pharmacy and Science, 2019
Levofloxacin (LVFX), a broad-spectrum antibacterial agent from the fluoroquinolone family, is universally prescribed with antipyretics, including paracetamol (APAP) analogs.
T. Shinozaki   +3 more
semanticscholar   +1 more source

Thermally Activated Delayed Fluorescence in an Organic Cocrystal: Narrowing the Singlet-Triplet Energy Gap via Charge Transfer.

Angewandte Chemie, 2019
Harvesting non-emissive spin-triplet charge-transfer (CT) excitons of organic semiconductors is fundamentally important for increasing the operation efficiency of future devices. We observed thermally activated delayed fluorescence (TADF) in a 1:2 charge
Lingjie Sun   +10 more
semanticscholar   +1 more source

Energetic Cocrystals

2023
Chaoyang Zhang, Jing Huang, Rupeng Bu
openaire   +1 more source

Cocrystals Definitions

Supramolecular Chemistry, 2007
F. LARA-OCHOA, G. ESPINOSA-PÉREZ
openaire   +1 more source

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