Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Organic Electrochemical Transistors for Real-Time Detection of Immune System Early Activation during Atezolizumab-Bevacizumab Treatment in Hepatocellular Carcinoma. [PDF]
Decataldo F +8 more
europepmc +1 more source
Electroactive Microbiomes: Electron Transfer Mechanisms and Environmental Biotechnology Applications
Electroactive microbiomes couple direct, mediated, conductive, and interspecies electron transfer with biofilm organisation to drive wastewater treatment, bioremediation, resource recovery, carbon conversion, and biosensing. Their performance depends on balancing electron transfer, mass transport, community structure, and electrode–biofilm interactions
Timoth Mkilima
wiley +1 more source
Reciprocal cross-feeding between bacteria can limit the emergence of metabolic dependencies. [PDF]
Chuang Y-C +8 more
europepmc +1 more source
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa +5 more
wiley +1 more source
Enhancements of symbiotic adhesion and antibiotic efficacy observed by the metabolic crosstalk within cell-bacteria cocultured on a microfluidic gut chip. [PDF]
Li J +8 more
europepmc +1 more source
MR identified phenylalanine as a causal PC risk factor (OR 1.18). A 5‐gene RF model (AUC 0.955) highlighted SLC6A14 as the top biomarker. Single‐cell analysis revealed epithelial–immune crosstalk. Molecular docking identified genistein (−9.1 kcal/mol) as a lead SLC6A14‐targeting compound.
Xing Liu +3 more
wiley +1 more source
Three-Dimensional Culture of Primary Hepatocytes in a Single-Cell Layer on Poly(vinyl alcohol) Nanofibrous Membrane. [PDF]
Tran HVA +6 more
europepmc +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Desorption Electrospray Ionization-Mass Spectrometry Imaging Provides Spatiochemical Information on Potential Biocontrol Agents against <i>Phytophthora capsici</i> Infection in Tomato Plants. [PDF]
Robinson JY +6 more
europepmc +1 more source

