Results 61 to 70 of about 2,599,751 (310)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Algorithms for Various Trigonometric Power Sums
AlgorithmsIn this paper, algorithms for different types of trigonometric power sums are developed and presented. Although interesting in their own right, these trigonometric power sums arise during the creation of an algorithm for the four types of twisted ...
Victor Kowalenko
doaj +1 more source
Alaska Criminal Code Revision — Tentative Draft, Part 4: Conspiracy; Criminal Mischief; Business and Commercial Offenses; Escape and Related Offenses; Offenses Relating to Judicial and Other Proceedings; Obstruction of Public Administration; Prostitution; Gambling [PDF]
, 1977 As of 1975, Alaska’s criminal laws were based primarily on Oregon criminal statutes as they existed at the close of the nineteenth century, with new statutes added and old statutes amended over the succeeding 75 years by Alaska territorial and state ...
Alaska Criminal Code Revision Subcommission
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
On coding morphisms for zigzag codes [PDF]
RAIRO - Theoretical Informatics and Applications, 1992 Summary: We are dealing with the zigzag codes in connection with monoid morphisms and free group morphisms. The injectivity of free group morphisms plays here the role of that of free monoid morphisms for ordinary codes. Subsets of free group words describing behaviours of zigzag factorizations allows us to characterize zigzag codes in different ways ...
Do Long Van +2 more
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Comparative Review of Lift Maintenance Regulations in Beijing, Hong Kong, and London
BuildingsLifts, or elevators, are transportation facilities that are indispensable for countless end users in high-rise buildings. They require proper maintenance to ensure safe operation.
Savannah Y. T. Lai +5 more
doaj +1 more source
SATT: Tailoring code metric thresholds for different software architectures
, 2016 Code metric analysis is a well-known approach for assessing the quality of a software system. However, current tools and techniques do not take the system architecture (e.g., MVC, Android) into account. This means that all classes are assessed similarly,
Treude, Christoph (author) +21 more
core +1 more source