Results 91 to 100 of about 1,735,552 (292)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Summary of Token-based Source Code Clone Detection Techniques [PDF]
Jisuanji kexueCode cloning refers to the generation of similar or identical code during software development due to the reuse,modification,and refactoring of source code.Code cloning has a positive impact on improving software development efficiency and redu-cing ...
LIU Chunling, QI Xuyan, TANG Yonghe, SUN Xuekai, LI Qinghao, ZHANG Yu
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A Member of the International Code Family Internationall Plumbling Code
, 2006 The I~zt~rr~c~tioPrlr1a~l1 rzbir1Cgo de is kept up to date through thc review of proposed changcs submitted by codc enSo~-cingo fficials,industry rcprescntatives, design professionals and other interested parties.
International Code Council
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
VulWeitor: a system for clone vulnerability detection using weighted code
CybersecurityDetecting and locating clone vulnerabilities in source code is essential for software maintenance and evolution. Although researchers have proposed many methods and tools for clone vulnerability detection, traditional methods fail to consider the ...
Shirun Liu, Aimin Yu, Zhengkai Qin
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
PLoS ONECode clones, referring to code fragments that are either similar or identical and are copied and pasted within software systems, have negative effects on both software quality and maintenance.
Fahmi H Quradaa +2 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
DeepClone: Modeling Clones to Generate Code Predictions
, 2020 Programmers often reuse code from source code repositories to reduce the development effort. Code clones are candidates for reuse in exploratory or rapid development, as they represent often repeated functionality in software systems.
Abdul Basit, Hamid +7 more
core +1 more source