Results 51 to 60 of about 115,619 (216)
Design and code coupling assessment based on defects prediction. Part 1 [PDF]
The article discusses an application of code metrics at object-oriented software design. Code metrics give an additional method to avoid errors except the obvious ones like thorough requirements, design, programming, testing, and consumer's feedback ...
Arwa Abu Asad, Izzat Alsmadi
doaj
Control Rod Drop Accident Analysis Based on Three-dimensional Coupling Analysis Code
The challenge for future nuclear fuel management research is to deal with the problems caused by the high nuclear fuel burnup, high power factor, and high enrichment of fuel assemblies.
HE Qingyun;CHEN Jun;MA Zhongying;PENG Sitao;LI Jinggang
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The China Fusion Engineering Test Reactor (CFETR) is a tokamak device to validate and demonstrate fusion engineering technology. In CFETR, the breeding blanket is a vital important component that is closely related to the performance and safety of the ...
Tao Dai +4 more
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A general description of mutual coupling in finite and infinite antenna arrays is provided and an open-source code is described for the analysis of mutual coupling in linear arrays of parallel dipoles.
Christophe Craeye +3 more
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source

