Results 51 to 60 of about 2,037,717 (291)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Model based code generation for distributed embedded systems [PDF]
, 2010 Embedded systems are becoming increasingly complex and more distributed. Cost and quality requirements necessitate reuse of the functional software components for multiple deployment architectures.
Delange, Julien +4 more
core +1 more source
Code Generation for Generally Mapped Finite Elements [PDF]
ACM Transactions on Mathematical Software, 2019 Many classical finite elements such as the Argyris and Bell elements have long been absent from high-level PDE software. Building on recent theoretical work, we describe how to implement very general finite-element transformations in FInAT and hence into the Firedrake finite-element system.
Kirby, Robert C., Mitchell, Lawrence
openaire +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
On the variable capacity property of CC/DS-CDMA systems [PDF]
, 2006 A complete complementary code based direct sequence code division multiple access (CC/DS-CDMA) system has been proposed recently as a potential candidate for beyond third generation (B3G) wireless communications.
Chen, HH, Song, YH, Wang, LP, Yang, Y
core +1 more source
Generalized PCM Coding of Images [PDF]
IEEE Transactions on Image Processing, 2012 Pulse-code modulation (PCM) with embedded quantization allows the rate of the PCM bitstream to be reduced by simply removing a fixed number of least significant bits from each codeword. Although this source coding technique is extremely simple, it has a poor coding efficiency. In this paper, we present a generalized PCM (GPCM) algorithm for images that
Prades Nebot, José +2 more
openaire +4 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
From product codes to structured generalized LDPC codes [PDF]
Proceedings of the 5th International ICST Conference on Communications and Networking in China, 2010 Product codes, due to their relatively large minimum distance, are often seen as a natural solution for applications requiring low error floors. In this paper, we show by means of an ensemble weight enumerator analysis that the minimum distance multiplicities of product codes are much higher than those obtainable by other generalized LDPC (GLDPC ...
M. Lentmaier +3 more
openaire +5 more sources