Results 191 to 200 of about 161,467 (336)
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv +29 more
wiley +1 more source
Respiratory health outcomes of children and adolescents exposed to wildfire smoke: a systematic review. [PDF]
Walters MK, Ward TJ.
europepmc +1 more source
Cryo‐EM analysis reveals an asymmetric MMOH–MMOB complex with distinct protomers, where MMOB binding triggers structural rearrangements from the surface to the active site. This conformational asymmetry shortens the Fe···Fe distance to 2.7 Å in one protomer, forming a geometry suitable for O2 activation and supporting a sequential catalytic mechanism ...
Yunha Hwang +9 more
wiley +1 more source
Epidemiological and digital syndromic surveillance data on dengue, chikungunya, and SARI in Brazil. [PDF]
Borges ME +3 more
europepmc +1 more source
A bioinspired TENG features a homologously paired interface with matched modulus. Ultrasonic cavitation enhances its toughness to 190 N m−1 (3.2× higher), preventing delamination under 400% strain. Abstract With the growing demand for flexible self‐powered energy sources for wearable bioelectronics, triboelectric nanogenerator (TENG) have emerged as a ...
Shiwei Xu +7 more
wiley +1 more source
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Evaluating Google Trends as a proxy for symptom incidence: insights from the winter COVID-19 infection study in England 2023/24. [PDF]
Asplin P +4 more
europepmc +1 more source

