Results 51 to 60 of about 184,131 (297)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Coded Modulation for Satellite Broadcasting [PDF]

open access: yes, 1996
In this paper, three-level block coded 8-PSK modulations, suitable for satellite broadcasting of digital TV signals, are presented. A design principle to achieve unequal error protection is introduced. The coding scheme is designed in such a way that the
Fossorier, Marc P. C.   +4 more
core   +1 more source

Maximum Euclidean distance network coded modulation for asymmetric decode-and-forward two-way relaying

open access: yes, 2013
Network coding (NC) compresses two traffic flows with the aid of low-complexity algebraic operations, hence holds the potential of significantly improving both the efficiency of wireless two-way relaying, where each receiver is collocated with a ...
Cao, Zhigang, Chen, Wei, Hanzo, Lajos
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Nonbinary LDPC-Coded Mode-Multiplexed Coherent Optical OFDM 1.28-Tbit/s 16-QAM Signal Transmission Over 2000 km of Few-Mode Fibers With Mode-Dependent Loss

open access: yesIEEE Photonics Journal, 2012
We demonstrate the possibility of nonbinary LDPC-coded mode-multiplexed coherent optical OFDM 1.28-Tbit/s 16-QAM signal transmission over 2000 km of few-mode fiber (FMF) with mode-dependent loss (MDL) by using an advanced mode-coupling compensation ...
Changyu Lin   +4 more
doaj   +1 more source

Codeword-Independent Performance of Nonbinary Linear Codes Under Linear-Programming and Sum-Product Decoding

open access: yes, 2008
A coded modulation system is considered in which nonbinary coded symbols are mapped directly to nonbinary modulation signals. It is proved that if the modulator-channel combination satisfies a particular symmetry condition, the codeword error rate ...
Flanagan, Mark F.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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