Results 71 to 80 of about 928,630 (288)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Capacity-Approaching Non-Binary Turbo Codes: A Hybrid Design Based on EXIT Charts and Union Bounds

open access: yesIEEE Access, 2018
In this paper, we introduce a novel design approach for capacity-approaching non-binary turbo codes. There are two important factors that impact the performance of turbo codes in general: 1) the convergence behavior of iterative decoding in the low ...
Toshiki Matsumine, Hideki Ochiai
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Error analysis for face coded modulation system

open access: yesIET Communications
This paper discusses a new mapping scheme known as face coded modulation (FCM) system. In FCM, peak energy symbols are mapped onto an innermost ring according to the eight sockets in the human face, that is, brain, mouth, nostrils, eyes and ears.
Peter O. Akuon
doaj   +1 more source

A Serial Concatenation of Binary-Input Nonbinary-Output Convolutional Code and Recursive Convolutional Lattice Code

open access: yesIEEE Access, 2018
The recently proposed recursive convolutional lattice code (RCLC) can form a signal with pseudo-Gaussian constellations, and their parallel concatenation is shown to approach the Shannon limit.
Toshiki Matsumine, Hideki Ochiai
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Near-capacity turbo trellis coded modulation design based on EXIT charts and union bounds

open access: yes, 2008
Bandwidth efficient parallel-concatenated Turbo Trellis Coded Modulation (TTCM) schemes were designed for communicating over uncorrelated Rayleigh fading channels.
Alamri, Osamah   +4 more
core   +1 more source

On combined coding and modulation. [PDF]

open access: yes, 2010
In the treatment of channel coding as a separate operation independent of the modulation, the coded set of sequences generally has a smaller channel symbol duration than the uncoded set of sequences for the same information rate. Accordingly, the power spectrum density (PSD) of the channel signals changes essentially.
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Turbo trellis-coded hierarchical modulation assisted decode-and-forward cooperation

open access: yes
Hierarchical modulation, which is also known as layered modulation, has been widely adopted across the telecommunication industry. Its strict backward compatibility with single-layer modems and its low complexity facilitate the seamless upgrading of ...
Ng, Soon Xin, Hanzo, Lajos, Sun, Hua
core   +1 more source

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