Results 121 to 130 of about 43,406 (144)
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Codeine Intoxication in the Neonate
Pediatrics, 1999Although opiates can provide patients with relief from pain and the discomfort of cough, the routine prescription of these drugs for infants demands caution and concern. Infants, particularly neonates, are not merely small adults requiring smaller dosages, but rather uniquely different patients.
Richard Evans, Barbarajean Magnani
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Codeine and the Breastfed Neonate
Journal of Human Lactation, 1993Codeine is an analgesic commonly used to relieve pain in the early post partum. Its metabolite, morphine, is probably responsible for its effectiveness in this use. However, morphine may also cause neonatal apnea. We studied free codeine and morphine levels inbreastmilk of 17 samples from seven mothers and neonatal plasma of 24 samples from 11 healthy,
Eric G. Naumburg +4 more
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Determination of Codeine in Terpin Hydrate and Codeine Elixir
Journal of Pharmaceutical Sciences, 1966Ion exchange chromatography and non-aqueous titrimetry are applied to the analysis of codeine in terpin hydrate and codeine elixir. The method is simple and accurate.
Martin I. Blake, Bruce Carlstedt
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The Journal of Clinical Pharmacology, 1994
The authors compared, in a double‐blind, randomized, crossover study in 13 healthy adult volunteers, the single‐ and multiple‐dose pharmacokinetics, relative bioavailability, and side effects of a new oral sustained‐release formulation of codeine (SRC) containing 150 mg codeine base, with oral immediate‐release codeine phosphate (IRC).
Andrew J. Coldman +5 more
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The authors compared, in a double‐blind, randomized, crossover study in 13 healthy adult volunteers, the single‐ and multiple‐dose pharmacokinetics, relative bioavailability, and side effects of a new oral sustained‐release formulation of codeine (SRC) containing 150 mg codeine base, with oral immediate‐release codeine phosphate (IRC).
Andrew J. Coldman +5 more
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JAMA: The Journal of the American Medical Association, 1935
To the Editor:— InThe Journal, March 24, 1934, page 908, was an article by Drs. Scheer and Keil reporting a case of hypersensitiveness to codeine and stating that there were only seven proved cases on record. Since then I have seen no new reports, so I am reporting a case of mine which I think is a proved case. It made no impression on me at that time
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To the Editor:— InThe Journal, March 24, 1934, page 908, was an article by Drs. Scheer and Keil reporting a case of hypersensitiveness to codeine and stating that there were only seven proved cases on record. Since then I have seen no new reports, so I am reporting a case of mine which I think is a proved case. It made no impression on me at that time
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2015
This case discusses the pharmacokinetic interaction between codeine and quinidine. Codeine is a prodrug, metabolized to the active compound morphine by CYP2D6, quinidine is a 2D6 inhibitor.
Clint Christensen +2 more
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This case discusses the pharmacokinetic interaction between codeine and quinidine. Codeine is a prodrug, metabolized to the active compound morphine by CYP2D6, quinidine is a 2D6 inhibitor.
Clint Christensen +2 more
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Codeine Intoxication in Infancy
New England Journal of Medicine, 1961CODEINE preparations, widely used for the symptomatic treatment of diseases in infants and children, are safe and effective agents in cases selected and controlled, with administration in the recom...
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