Results 141 to 150 of about 27,730 (240)

Extended‐release buprenorphine in adults with opioid use disorder involving poppy seed tea: An 18‐month retrospective case series

The American Journal on Addictions, Volume 35, Issue 5, Page 638-642, September 2026.
Abstract Background and Objectives Poppy seed tea (PST) contains unpredictable opioid concentrations, destabilising tolerance and increasing overdose risk. Extended‐release buprenorphine (BUP‐XR) provides sustained coverage without daily dosing. Methods Eighteen‐month follow‐up of adults (N = 3) with opioid use disorder (OUD) involving PST in Australia.
John McMaster, Saumiya Seshakumaran, Hesitha Abeysundera, Isha Tipirneni, Rita Hormiz   +4 more
wiley   +1 more source

The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Introduction 37%–48% of older patients receive anticholinergic medicines, increasing the risk for falls, delirium, dementia and death. Hospital admission may provide an opportunity for deprescribing to improve outcomes. This study evaluated the feasibility and acceptability of a digital tool to identify anticholinergic medicines and support ...
Kinda Ibrahim, Eloise Radcliffe, Edward Hewertson, Andrew Bates, Andy Fox, Emily Smith, Cathrine Mckenzie, Liam Jones, Sara Mckelvie, Ngianga Ii Kandala, Sara McCloskey, Tracey Sach, Stephen Lim   +12 more
wiley   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Non‐Prescribed Gabapentinoid Use: Demographic and Behavioural Risk Profiles in a Large International Sample

Drug and Alcohol Review, Volume 45, Issue 6, September 2026.
ABSTRACT Introduction The harm potential of gabapentinoids is well established, with concerns about non‐medical use increasing alongside prescribing rates. However, less is known about the characteristics of people who use gabapentinoids obtained through non‐prescribed routes.
Jennifer Seddon, Monica J. Barratt, Cheneal Puljević, Jason A. Ferris, Adam R. Winstock, Emma L. Davies   +5 more
wiley   +1 more source

Methodological Concerns Regarding Codeine and Oxycodone Safety Comparisons in Hip Osteoarthritis [Response to Letter]. [PDF]

Drug Des Devel Ther
Lee J, Kim Y, Choo E, Shin S, Choi YJ.
europepmc   +1 more source

Growth hormone replacement therapy induces codeine clearance

, 2002
The increasing clinical use of growth hormone (GH) has raised questions about other than growth-related metabolic effects of this treatment. GH regulates the expression of several hepatic drug metabolising enzymes in the rat, but it is not known whether ...
Bengtsson, B-A, Johannsson, Gudmundur,, Rane, A, Gil Berglund, E, Beck, O   +4 more
core  

Fentanyl Detection in Biological Samples From Individuals Reporting Synthetic Cannabinoid Use in São Paulo, Brazil

Drug and Alcohol Review, Volume 45, Issue 6, September 2026.
ABSTRACT Introduction Brazil has historically exhibited low illicit opioid prevalence, though forensic data indicate rising fentanyl seizures, often in combination with other substances. People who use Synthetic cannabinoid receptor agonists (SCRA) are particularly vulnerable to unintentional fentanyl exposure due to the unpredictable chemical ...
Ligia Goes Endo, Rodrigo Alves de Oliveira, Ivan Dieb Miziara, Mauricio Yonamine, João Maurício Castaldelli‐Maia, Vilma Leyton, Henrique Silva Bombana   +6 more
wiley   +1 more source

Methodological Concerns Regarding Codeine and Oxycodone Safety Comparisons in Hip Osteoarthritis [Letter]. [PDF]

Drug Des Devel Ther
Shan J, Chen K, Cen Y.
europepmc   +1 more source

Pharmacogenomics and Opioid Efficacy in Sickle Cell Disease: Is the Field Ready for Precision Prescribing? [PDF]

J Pers Med
Jaja C, Sop DM, Campbell A, Smith WR.
europepmc   +1 more source

Computational Insights into the Molecular Synergy of Paracetamol and Codeine. [PDF]

Life (Basel)
Amzoiu MO, Popescu GS, Amzoiu DC, Ciocîlteu MV, Rau G, Manda CV, Gresita A, Taisescu O.   +7 more
europepmc   +1 more source