Results 101 to 110 of about 916,424 (298)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

RELACIÓN CIRCULAR ENTRE ÉTICA, RESPONSABILIDAD SOCIAL Y REPUTACIÓN DE LAS COOPERATIVAS / CIRCULAR RELATIONSHIP AMONG ETHIC, SOCIAL RESPONSIBILITY AND REPUTATION OF COOPERATIVES [PDF]

open access: yesRevista de Estudios Cooperativos, 2012
De forma progresiva, las empresas implantan programas y actividades sobre la base de la ética empresarial, la responsabilidad social y el buen gobierno, una estrategia justificada tanto por las actuales presiones procedentes de la sociedad como por los ...
Isabel OLMEDO CIFUENTES   +3 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Gender and ethical trade: A mapping of the issues in African horticulture [PDF]

open access: yes, 2001
Codes of conduct covering employment conditions of Southern producers exporting to European markets mushroomed throughout the 1990s. A recent article (Blowfield 2000) cited over 200 codes related to worker welface specifically, and over twenty codes ...
Barrientos, Stephanie   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Forest Certification: Toward Common Standards? [PDF]

open access: yes
The forestry industry provides a good illustration of the active roles that industry associations, environmental nongovernmental organizations (NGOs), national governments, and international organizations can play in developing and promoting codes of ...
Aguilar , Francisco   +3 more
core  

The Rise of the Code of Conduct in Japan: Legal Analysis and Prospect [PDF]

open access: yes, 2004
A code of conduct is a set of rules adopted by transnational corporations (“TNCs”) to regulate mainly working conditions and the management of contract factories.
Ishikawa, Koji
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Was the Adoption of Codes of Conduct by the Transnational Companies Effective for the Bringing to an End of Apartheid in South Africa? [PDF]

open access: yesRevista CIDOB d'Afers Internacionals, 1995
The international community frequently imposes sanctions of an economic character on those countries which blatantly violate the most fundamental human rights. This article intends to analyse other possible sanction mechanisms: the codes of conduct.
Olga Estadella Yuste
doaj  

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