Results 111 to 120 of about 166,150,737 (295)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Do companies walk the talk? Commitments and actions in global supply chain labor standards

International Journal of Corporate Social Responsibility
This article examines the efforts towards implementing minimum labor standards in global supply chains through the lens of corporate social responsibility.
Sarah Vandenbroucke, Helen Pluut, Yvonne Erkens, Jaroslaw Kantorowicz   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Making researchers responsible: attributions of responsibility and ambiguous notions of culture in research codes of conduct. [PDF]

BMC Med Ethics, 2020
Valkenburg G, Dix G, Tijdink J, de Rijcke S.   +3 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Corporate social responsibility (CSR) in transnational spaces: an institutionalist deconstruction of MNC's CSR practices in the Nigerian oil and gas sector [PDF]

, 2008
Drawing from the varieties of capitalism theoretical framework, the study explores the home country influences of MNCs on their CSR practices when they operate outside their national/regional institutional contexts.
Amaeshi, Kenneth, Amao, Olufemi O.
core  

Cyclic codes over Z4 of even length

, 2006
We determine the structure of cyclic codes over Z 4 for arbitrary even length giving the generator polynomial for these codes. We determine the number of cyclic codes for a given length.
Dougherty, Steven T., Ling, San
core   +1 more source

Brief research report: development of codes of conduct in online classrooms for Vietnamese high school students

Frontiers in Education
BackgroundIn today's digital age, online education helps eliminate certain barriers faced by traditional education, however, it also presents challenges, including issues related to the culture of conduct among high school students in their relationships
Bui Thanh Thuy, Xuan-An Nguyen, Nguyen Thi Viet Ha, Vo Thanh Ha, Nguyen Thi Kieu Anh, Do Thi Ngoc Hien   +5 more
doaj   +1 more source