Results 101 to 110 of about 173,495,554 (293)
VALUE CREATION THROUGH CORPORATE GOVERNANCE [PDF]
Companies spend time and money in order to improve their corporate governance (CG) system and also do not forget to inform third parties about their efforts in this field.
Elena Chitimus
doaj
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Australians face a complex, confusing and often inconsistent environment when it comes to regulating how businesses and consumers should conduct themselves online.This report examines 16 codes of conduct that are relevant to Australian consumers when ...
David Vaile, Chris Connolly
core
The European Union’s General Data Protection Regulation (GDPR) encourages the development of ‘codes of conduct’ in its articles 40-41. Although institutional actors and corporate stakeholders have expressed great interest in such tools, there are still ...
Vander Maelen, Carl
core
The OBF Code of Conduct was adopted after being voted on by our members in January 2022, following the OBF Public Board meeting in September 2021. Our annual conference, BOSC, is normally run as part of the ISMB meeting, where it therefore follows the OBF Code of Conduct.
openaire +2 more sources
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source

