Results 51 to 60 of about 241,954 (329)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Un code à décoder : le futur code civil chinois [PDF]
, 2005 Depuis la réouverture de la Chine à l’Occident en 1978, le législateur chinois fonde largement les réformes juridiques sur les transferts de droit. C’est dans ce contexte qu’il faut situer, entre autres, le dépôt d’un projet de code civil chinois le 24 ...
Piquet, Hélène
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
La codification des lois civiles au Bas-Canada et l'idée de loi naturelle [PDF]
, 1993 Le présent article essaie de délimiter de la manière la plus précise possible le rôle de la notion de loi naturelle dans le cadre de l'opération de codification des lois civiles au Bas-Canada.
LaRue, Richard
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Designing a product service system in a social framework: methodological and ethical considerations [PDF]
, 2009 Macroscopic social and economic changes in the last few years are forcing business companies and public institutions to redefine their approach to social intervention, focusing on local and highly individualised solutions. This change is also calling for
Jonas, Wolfgang +2 more
core
Improving Spatial Codification in Semantic Segmentation [PDF]
, 2015 This paper explores novel approaches for improving the spatial codification for the pooling of local descriptors to solve the semantic segmentation problem.
Giró-i-Nieto, Xavier +5 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
ReligionsThis article presents a historiographical survey of scholarship on Islamic law and legal authority in Central/Inner Asia under Russian Imperial rule. It analyzes the debates, paradigms and assumptions that have dominated the field up to the present.
Rozaliya Garipova
doaj +1 more source
FROM THE POLISH WORKS ON THE CODIFICATION OF JUDICIAL PRINCIPLES OF CONDUCT [PDF]
Studia Warmińskie, 2017 In the article the author depicts the process of creating the codification of judicial principles of professional conduct. Firstly, the author describes the beginnings of the “model of a good judge”, followed thereafter by discussion in judicial ...
Korzeniewska-Lasota Anna
doaj