Results 71 to 80 of about 40,508 (295)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
International Codification: Challenges and Perils [PDF]
, 2023 This tribute to Professor Emeritus Tony Smith considers the codification of international law, particularly international criminal law, given Tony's long-term commitment to criminal law.
Keith, KJ
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Tipologi Kitab Al-Ma'ajim dalam Kodifikasi Hadis
Riwayah: Jurnal Studi Hadis, 2018 The method which is used by theologian in hadi>th codification has a trend that change from time to time. After third century of hijriyah, some theologians arrange hadith’s book using the method that has already taught to them before, but others have a ...
Muhammad Khudhori
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Internal versus External Labour Flexibility : The Role of Knowledge Codification. [PDF]
This article uses a competence-based approach to the firm in order to analyse the recent destabilisation of internal labour markets. We argue that increasing knowledge codification made possible by the diffusion of information and communication ...
Caroli, Eve
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Enhancing the Codification of Crimes Against Humanity: A Neutrosophic and Analytical Approach to International Legal Frameworks [PDF]
Neutrosophic Sets and SystemsThe present paper investigates the process of codifying crimes against humanity, with a specific focus on the difficulties encountered in achieving regulatory consistency and precision within international legal traditions.
Marcia Esther España Heredia +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
To Know is to Be: Three Perspectives on the Codification of Knowledge [PDF]
This paper presents three perspectives on the codification of knowledge. These perspectives are formed by recent contributions in the fields of economics, business and management studies and of a group of writers who have a ‘relational’ perspective from ...
Mike Bartholomaei
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Les fondements historiques du droit européen des affaires
, 2021 Le droit européen des affaires est aujourd'hui appréhendé essentiellement dans sa dimension économique et fiscale au travers notamment de l'union douanière.
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