Results 91 to 100 of about 40,508 (295)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Le volet maritime du Code des Transports : une nouvelle Ordonnance de la Marine ? [PDF]

open access: yes
La France vient de se doter de son premier Code des Transports, entré en vigueur le 1er décembre 2010, et dont toute une partie est consacrée aux transports et à la navigation maritimes.
Pierre Angelelli
core  

MODERNIZING THE PRIVATE LAW. SOME KEY ISSUES IN THE RECENT DRAFT OF THE SPANISH COMMERCIAL CODE [PDF]

open access: yesChallenges of the Knowledge Society, 2016
The last decades were dominated by the idea that an authentic process to modernize the private law means generally the unification of it by renouncing the distinction between civil and commercial law.
Dan VELICU
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Environmental Law Codification in China: Paradigm Change in Environmental Legislation

open access: yes
This book emerges from a series of research seminars and projects conducted over seven years at prestigious Chinese law schools and environmental research institutes, focusing on the formulation of an Environmental Code in China.
Zhao, Xiaobo.   +7 more
core   +1 more source

Effet de codification et interprétation

open access: yes, 1986
Une codification réussie des lois civiles produit un effet de codification porteur d’une orientation générale d’interprétation amplifiante. Manifestement voulu par les codificateurs québécois de 1866, l’effet de codification a montré des signes de ...
Bisson, Alain-François
core   +1 more source

Item codification

open access: yes, 2020
Item codification from the research: Smart devices fostering smart learning education: A comparative study among Spanish and Latin American higher education ...
Ana Pérez-Escoda (6806024)   +2 more
core   +1 more source

On the Prospects of Civil Law Codification in the Former Yugoslav Republics

open access: yesМосковский журнал международного права
INTRODUCTION. The article analyses the prospects for the codification of civil law in the states that emerged on the territory of the former Yugoslavia within the framework of the Romano‑Germanic legal family and contemporary trends towards systematic ...
E. Yu. Matveeva
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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