Results 91 to 100 of about 29,557 (302)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Item codification

open access: yes, 2020
Item codification from the research: Smart devices fostering smart learning education: A comparative study among Spanish and Latin American higher education ...
Ana Pérez-Escoda (6806024)   +2 more
core   +1 more source

Les enjeux de la codification en France [PDF]

open access: yes, 2005
La France, patrie des codes, connaît actuellement une grande effervescence en matière de codification, tant au sein des pouvoirs publics qu’en doctrine. Depuis une cinquantaine d’années, un vaste mouvement de codification à droit constant a été entrepris,
Rémy Cabrillac, Cabrillac, Rémy
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Le volet maritime du Code des Transports : une nouvelle Ordonnance de la Marine ? [PDF]

open access: yes
La France vient de se doter de son premier Code des Transports, entré en vigueur le 1er décembre 2010, et dont toute une partie est consacrée aux transports et à la navigation maritimes.
Pierre Angelelli
core  

Environmental Law Codification in China: Paradigm Change in Environmental Legislation

open access: yes
This book emerges from a series of research seminars and projects conducted over seven years at prestigious Chinese law schools and environmental research institutes, focusing on the formulation of an Environmental Code in China.
Zhao, Xiaobo.   +7 more
core   +1 more source

Effet de codification et interprétation

open access: yes, 1986
Une codification réussie des lois civiles produit un effet de codification porteur d’une orientation générale d’interprétation amplifiante. Manifestement voulu par les codificateurs québécois de 1866, l’effet de codification a montré des signes de ...
Bisson, Alain-François
core   +1 more source

On the Concept of the New Code of the Russian Federation on Administrative Responsibility: A Brief Commentary on the Bill

open access: yesСибирское юридическое обозрение, 2020
The article comments on the draft Concept of the new Code of the Russian Federation on Administrative Responsibility. It is emphasized that the Concept maintains and develops traditional approaches to the legal regulation of relations that make up the ...
V. E. Sevryugin
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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