Results 111 to 120 of about 29,557 (302)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Mart 2022 Tarihli Fransız Milletlerarası Özel Hukuk Kanunu Tasarısının Genel Hükümlerine Dair Bazı Tespitler

open access: yesSakarya Üniversitesi Hukuk Fakültesi Dergisi/Sakarya Hukuk Dergisi
Türk hukukuna bugüne değin örnek teşkil etmiş hukuk düzenlerinden olan Fransız hukukunda 2024 yılı itibariyle halen bağımsız bir milletlerarası özel hukuk kanunu bulunmamaktadır. 20.
Can Yöney
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Editorial : Codification(s)

open access: yes, 1990
Editorial : Codification(s). In: Politix, vol. 3, n°10-11, Deuxième et troisième trimestre 1990. Codification(s) sous la direction de Bastien François et Jean-Philippe Heurtin.

core   +1 more source

Efficiency of the categorization of the public procurement contracts [PDF]

open access: yesCivilizar, 2010
The French public procurement contracts at large, including the public markets - public Works or services contracts – the delegation public service, public-private partnership contract or even the administrative emphyteutic lease are close as these ...
Edwin Tachlian
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Codification of Croatian prosody

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2004
The article discusses codification of Croatian prosody. Particular attention is given to prestige and neutrality that influence the social acceptability of the accent and standard language.
Krešimir Mićanović
doaj  

Les normes dans leur diversité. Quelle pertinence ? [PDF]

open access: yesEcho des Etudes Romanes, 2015
The concept of norm is particularly ambiguous in French. It can refer to official, objective, subjective, regional, popular standards, etc. Therefore the objective of this paper is to determine if these different standards have almost the same status
Feuillard Colette
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

International Codification: Challenges and Perils

open access: yes, 2023
This tribute to Professor Emeritus Tony Smith considers the codification of international law, particularly international criminal law, given Tony's long-term commitment to criminal law.
Keith, KJ
core  

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