Results 101 to 110 of about 186,635 (298)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Mart 2022 Tarihli Fransız Milletlerarası Özel Hukuk Kanunu Tasarısının Genel Hükümlerine Dair Bazı Tespitler

open access: yesSakarya Üniversitesi Hukuk Fakültesi Dergisi/Sakarya Hukuk Dergisi
Türk hukukuna bugüne değin örnek teşkil etmiş hukuk düzenlerinden olan Fransız hukukunda 2024 yılı itibariyle halen bağımsız bir milletlerarası özel hukuk kanunu bulunmamaktadır. 20.
Can Yöney
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Codification of Croatian prosody

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2004
The article discusses codification of Croatian prosody. Particular attention is given to prestige and neutrality that influence the social acceptability of the accent and standard language.
Krešimir Mićanović
doaj  

Efficiency of the categorization of the public procurement contracts [PDF]

open access: yesCivilizar, 2010
The French public procurement contracts at large, including the public markets - public Works or services contracts – the delegation public service, public-private partnership contract or even the administrative emphyteutic lease are close as these ...
Edwin Tachlian
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Codification [PDF]

open access: yesEuropean Review of Contract Law, 2012
openaire   +2 more sources

Les normes dans leur diversité. Quelle pertinence ? [PDF]

open access: yesEcho des Etudes Romanes, 2015
The concept of norm is particularly ambiguous in French. It can refer to official, objective, subjective, regional, popular standards, etc. Therefore the objective of this paper is to determine if these different standards have almost the same status
Feuillard Colette
doaj  

Burying Evidence\u27s Dead Hand [PDF]

open access: yes, 2019
When the Rhode Island Rules of Evidence were adopted, they displaced all inconsistent case law existing at the time. Though the Rules retain a great deal of the evidence practice that preceded them, there is much in evidence practice that changed with ...
Provencher, Matthew D.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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