Results 81 to 90 of about 40,508 (295)
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Codified-Tacit and General-Specific Knowledge in the division of labour among firms. A study of the Software Industry [PDF]
This paper addresses the organisation and codification of knowledge in the software industry. It analyses various economic incentives to codification, including the need to improve the productivity and quality of software production processes and to ...
Rosa Grimaldi, Salvatore Torrisi
core
Лемкiвскiй язык з перспектывы 30-лiтя
Lemko Language from a 30-Year Perspective From the very moment the Lemko Association was established in 1989, the promotion of Lemko language usage, primarily through schooling, has been one of its most important statutory goals.
Генрик ФОНТАНЬСКІЙ
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Knowledge Codification and Endogenous Growth
The usual models of endogenous growth treat knowledge codification as a byproduct of R&D and as costless. In contrast to this, one can observe great efforts of private firms for the purposeful codification of knowledge.
Schneider, Maik T., Maik T. Schneider
core +1 more source
The codification of civil law is the main foundation of the private law system in the civil law tradition. However, Indonesian civil law still relies on the Civil Code (KUHPerdata), which adopted the Dutch Burgerlijk Wetboek of 1838, and is therefore ...
Tina Amelia
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Les enjeux de la codification en France [PDF]
La France, patrie des codes, connaît actuellement une grande effervescence en matière de codification, tant au sein des pouvoirs publics qu’en doctrine. Depuis une cinquantaine d’années, un vaste mouvement de codification à droit constant a été entrepris,
Rémy Cabrillac, Cabrillac, Rémy
core +1 more source
Over the past forty years of reform and opening-up, China has experienced vigorous development of Intellectual Property Law. During this period, it has successively enacted and promulgated a range of basic laws, among which are the Trademark Law of ...
Wu Handong
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

