Results 131 to 140 of about 1,765,355 (377)

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Academics and Social Networking Sites: Benefits, Problems and Tensions in Professional Engagement with Online Networking [PDF]

, 2018
The web has had a profound effect on the ways people interact, with online social networks arguably playing an important role in changing or augmenting how we connect with others.
Bastian, Boyd, Boyer, Carrigan, Carrigan, Costa, Costa, Donelan, Gruzd, Hogan, Kimmons, Lorenzo-Romero, Lupton, Nature Publishing Group, Nentwich, Rainie, Shah, Singh, Stewart, Strauss, Veletsianos, Veletsianos, Weller   +22 more
core   +2 more sources

Facilitating informed choice about non-invasive prenatal testing (NIPT): a systematic review and qualitative meta-synthesis of women’s experiences

BMC Pregnancy and Childbirth, 2019
BackgroundNon-invasive prenatal testing (NIPT) can be used to accurately detect fetal chromosomal anomalies early in pregnancy by assessing cell-free fetal DNA present in maternal blood.
A. Cernat, Chanté De Freitas, Umair Majid, Forum Trivedi, C. Higgins, M. Vanstone   +5 more
semanticscholar   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Application of Qualitative Methods in Health Research: An Overview [PDF]

, 2010
Qualitative research is type of formative research that includes specialized techniques for obtaining in-depth responses about what people think and how they feel.
Deshmukh, PR, Dongre, AR, Kalaiselvan, G, Upadhyaya, S   +3 more
core   +1 more source

Sports review: A content analysis of the International Review for the Sociology of Sport, the Journal of Sport and Social Issues and the Sociology of Sport Journal across 25 years [PDF]

, 2014
The International Review for the Sociology of Sport, the Journal of Sport and Social Issues and Sociology of Sport Journal have individually and collectively been subject to a systematic content analysis.
Bishop R, Callinicos A, Carrington B, Collini S, David M, Heck J, Hussey T, Jon Dart, Krippendorff K, Lapchick R, Mills CW, Mumford S, Riffe D, Silverman D, Spender D, Stemple G, Thrift N   +16 more
core   +1 more source

Medication data collection and coding in a home-based survey of older adults.

The journals of gerontology. Series B, Psychological sciences and social sciences, 2009
OBJECTIVES To describe the collection, coding, and validity of medication data from the National Social Life, Health and Aging Project (NSHAP)-a survey of a national probability sample of adults aged 57-85 years.
D. Qato, L. P. Schumm, Michael Johnson, A. Mihai, S. Lindau   +4 more
semanticscholar   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Why the epistemologies of trust researchers matter [PDF]

, 2015
In this thought piece we take stock of and evaluate the nature of knowledge production in the field of trust research by examining the epistemologies of 167 leading trust scholars, who responded to a short survey.
Bachmann, Reinhard, Bristow, Alexandra, Isaeva, Neve, Saunders, Mark N.K.   +3 more
core   +2 more sources

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source