Multidimensional Gene Space as an Approach for Analyzing the Organization of Genomes. [PDF]
Zaytsev K, Bogatyreva N, Fedorov A.
europepmc +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Complete Mitochondrial Genome Sequencing of <i>Brachypelma albiceps</i> and Comparative Codon Usage Bias Analysis Across Seven Mygalomorphae Species. [PDF]
Zhan Q +7 more
europepmc +1 more source
Codon 10 Polymorphisms in the Transforming Growth Factor-Beta 1 Gene May Be Associated With the Predisposition to Idiopathic Pulmonary Fibrosis in Koreans [PDF]
Ji-Young Son +10 more
openalex +1 more source
Uncovering a new layer of translational control, this study reveals how TRMT6/TRMT61A‐mediated tRNA‐m1A methylation drives pro‐tumorigenic senescence in colorectal cancer. By selectively enhancing ARG2 translation, this epitranscriptomic axis triggers an NF‐κB‐dependent SASP.
Tuoyang Li +17 more
wiley +1 more source
Genomic and physiological signatures of adaptation in pathogenic fungi. [PDF]
Guerreiro MA +4 more
europepmc +1 more source
Die Sortierung von Membranproteinen: Der Einfluss der codon usage auf die Sortierung von Modell-Kaliumkanälen [PDF]
Marina Kithil
openalex +1 more source
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang +9 more
wiley +1 more source
Emerging roles of tRNA modification-mediated codon-specific translational reprogramming in cancer biology. [PDF]
Wang H, Zhang J, Jiang C, Xu S.
europepmc +1 more source

