Results 41 to 50 of about 350,704 (260)
On coefficients of $ \alpha$-Shapiro Shields functions
Tamkang Journal of Mathematics, 2002 We investigate the Taylor coefficients of $ \alpha$-Shapiro Shields functions and some applications to $ \alpha$-Bloch functions and Bergman functions are given.
Chern, T. Y. Peter, Wulan, Hasi
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Statistical Inference for Coefficient Alpha [PDF]
Applied Psychological Measurement, 1987 Rigorous comparison of the reliability coefficients of several tests or measurement procedures requires a sampling theory for the coefficients. This paper sum marizes the important aspects of the sampling theory for Cronbach's (1951) coefficient alpha, a widely used internal consistency coefficient.
Feldt, Leonard S. +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Products of graphs and Nordhaus-Gaddum type inequalities for eigenvalues [PDF]
Transactions on Combinatorics, 2018 In this paper, we obtain $alpha$ as coefficient for the $G=K_{alpha n} cup overline{K_{(1-alpha)n}}$ and by which we discuss Nikiforov's conjecture for $lambda_{1}$ and Aouchiche and Hansen's conjecture for $q_1$ in Nordhaus-Gaddum type inequalities.
Nastaran Keyvan, Farhad Rahmati
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Translation and localization the Persian version of diabetes distress scale among type 2 diabetes
Diabetology & Metabolic Syndrome, 2023 Introduction The aimed of this psychometric cross-sectional research was translation and localization the Persian version of diabetes distress scale in type 2 diabetes.
Alireza Jafari +4 more
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