Results 51 to 60 of about 352,776 (259)

Traumatic Memory of One’s Son Gone Missing in War: Content Analysis Using Krippendorff’s Alpha

SAGE Open, 2019
Our aim was to determine (a) how parents deal with experiences like having a son missing in war, and (b) what expectations they have in terms of outcomes. This qualitative study included 29 parents of 21 sons gone missing in war. We used content analysis
Slavica Kozina, Martin Kowalski, Mirela Vlastelica, Tonći Mastelić, Josip A. Borovac   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Translation and localization the Persian version of diabetes distress scale among type 2 diabetes

Diabetology & Metabolic Syndrome, 2023
Introduction The aimed of this psychometric cross-sectional research was translation and localization the Persian version of diabetes distress scale in type 2 diabetes.
Alireza Jafari, Hadi Tehrani, Mohammadjavad Mansourian, Mahbobeh Nejatian, Mahdi Gholian‑Aval   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Misuse and Misconception of Cronbach\'s Alpha Coefficient as an Index of Internal Consistency of Measuring Tools

مجله اپیدمیولوژی ایران, 2017
Calculation of Cronbachchr('39')s Alpha which measures the internal reliability of a tool is easy, but misuse and misconception are widely observed. Common misunderstandings of the Cronbachchr('39')s Alpha include inability to differentiate between being
R Pakzad, F Alaeddini
doaj  

The light CP-even MSSM Higgs mass resummed to fourth logarithmic order

European Physical Journal C: Particles and Fields, 2018
We present the calculation of the light neutral CP-even Higgs mass in the MSSM for a heavy SUSY spectrum by resumming enhanced terms through fourth logarithmic order (N$$^{3}$$ 3 LL), keeping terms of leading order in the top Yukawa coupling $$\alpha _t$$
R. V. Harlander, J. Klappert, A. D. Ochoa Franco, A. Voigt   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Reliability generalization meta-analysis of Cronbach’s alpha of the oral impacts on daily performance (OIDP) questionnaire

BMC Oral Health
Objective To evaluate the pooled estimates of Cronbach’s alpha of the Oral Impacts on Daily Performance (OIDP) questionnaire and explore the moderators that could have influenced the overall estimate.
Kalyana Chakravarthy Pentapati, Deepika Chenna, Vijay S. Kumar, Nanditha Kumar   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source