Results 121 to 130 of about 2,637,288 (262)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Logistic regression model coefficient estimates derived using Bayesian model averaging.
, 2016 Logistic regression model coefficient estimates derived using Bayesian model averaging.
Doo Yong Chung (616239) +8 more
core +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
On a New Subclass of Multivalent Harmonic Mappings Associated with Close-to-Convex Functions
MathematicsThis paper is devoted to defining and analyzing a new subclass M(ν,τ,q) of q-valent harmonic mappings in the unit disk D, as well as investigating its connection with close-to-convex analytic functions.
A. Alameer
doaj +1 more source
"The Economic Consequences of Weintraub's Consumption Coefficient" [PDF]
In this paper we show that Weintraub:s consumption coefficient (the ratio of total consumption to wages) can elucidate trends in the sectoral and functional distributions of income We also show that, in a Kaleckian model, it simplifies and add precision ...
Anthony J. Laramie +2 more
core
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Random coefficient regressions: parametric goodness of fit tests [PDF]
, 1995 Random coefficient regression models have been applied in different fields during recent years and they are a unifying frame for many statistical models.
Delicado, Pedro, Romo, Juan
core +1 more source
Statistical Data Compiled and Published by the Bureau of Crop Estimates, 1863-1920 [PDF]
Excerpts from the Foreword: The Bureau of Crop Estimates (Bureau of Statistics) has collected and compiled data relating to agriculture since its organization as a statistical division in the Patent Office in 1840, and has published such data in various ...
Bureau of Crop Estimates
core +1 more source