Results 121 to 130 of about 432,084 (315)
On a New Class of Concave Bi-Univalent Functions Associated with Bounded Boundary Rotation
MathematicsIn this research article, we introduce a new subclass of concave bi-univalent functions associated with bounded boundary rotation defined on an open unit disk. For this new class, we make an attempt to find the first two initial coefficient bounds.
Prathviraj Sharma +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2008 The Gini coefficient has proved valuable as a measure of income inequality. In cross-sectional studies of the Gini coefficient, information about the accuracy of its estimate is crucial.
Berger, Yves G.
core
Coefficient estimates arising from the geographically weighted regression example.
, 2016 Coefficient estimates arising from the geographically weighted regression example.
Ross S. Purves (3147369) +4 more
core +1 more source
Efficient Methods for the Estimation of Homogenized Coefficients [PDF]
Foundations of Computational Mathematics, 2018 45 pages, 6 ...
openaire +3 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
U-Estimators of Regression Coefficients
Journal of Multivariate Analysis, 1993 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Coefficient estimates and statistical analysis of the fitted model.
, 2014 Coefficient estimates and statistical analysis of the fitted model.
José Helvecio Martins (567621) +6 more
core +1 more source