Results 81 to 90 of about 1,548,203 (287)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Note on Estimated Coefficients in Random Effects Probit Models. [PDF]
This note points out to applied researchers what adjustments are needed to the coefficient estimates in a random effects probit model in order to make valid comparisons in terms of coefficient estimates and marginal effects across different ...
Arulampalam, W.
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Coefficient estimates for some classes of functions associated with \(q\)-function theory
, 2017 In this paper, for every $q\in(0,1)$, we obtain the Herglotz representation theorem and discuss the Bieberbach type problem for the class of $q$-convex functions of order $\alpha, 0\le ...
Agrawal, Sarita
core
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Some Classes of Harmonic Mapping with a Symmetric Conjecture Point Defined by Subordination
Mathematics, 2019 In the paper, we introduce some subclasses of harmonic mapping, the analytic part of which is related to general starlike (or convex) functions with a symmetric conjecture point defined by subordination.
Lina Ma, Shuhai Li, Xiaomeng Niu
doaj +1 more source
Experimental and theoretical aerodynamic characteristics of two hypersonic cruise aircraft concepts at Mach numbers of 2.96, 3.96, and 4.63 [PDF]
The longitudinal and lateral directional aerodynamic characteristics for two Mach 5 cruise aircraft concepts were determined for test Mach numbers of 2.96, 3.96, and 4.63.
Pittman, J. L., Riebe, G. D.
core +1 more source
L p Estimation of the Diffusion Coefficient
Bernoulli, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source