Results 71 to 80 of about 167,489,176 (300)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Learning new words: effects of meaning, memory consolidation, and sleep [PDF]
, 2010 Although encountering novel words in one's own language in adulthood is not an uncommon event, the relevant cognitive processes have become the target of systematic investigation only in recent years.
Tamminen, Jakke
core
Study on Consolidation Coefficient by Different Test Methods
, 2011 Through indoor consolidation test and CPTU model test and CPTU in-situ test, the soil consolidation coefficient has been studied. Compared with the consolidation coefficient by indoor test equipment and CPTU, because in-situ test has been made by CPTU ...
Yan Chun Tang +2 more
core +1 more source
Case history and back-analysis of large-scale embankment construction on peat using vacuum consolidation [PDF]
E3S Web of ConferencesThis presentation discusses engineering considerations for designing and constructing large-scale embankments on peat deposits in Hokkaido, northern Japan, using the vacuum consolidation method with Prefabricated Vertical Drains (PVDs).
Takahashi Hideaki +4 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A Contingency View of Consolidation Systems [PDF]
, 2009 A consolidation system is a type of an accounting information system that aims to facilitate the consolidation process of organisations that are comprised of a collection of entities, but that are required to produce one set of consolidated financial ...
SMITH, PIETER,RETIEF +1 more
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Coefficient of consolidation of sandy clay
, 2014 Consolidation is a major issue of geotechnical engineering due to its implications on ground settlement. Efficacy of remedial measures against excessive consolidation relies on understanding of factors affecting coefficient of consolidation. This project
Kusnadi, Andhi Wijaya Harja
core
Fiscal consolidation : Dr Pangloss meets Mr Keynes [PDF]
, 2013 A simple dynamic framework is used to show how consolidation plans that are robust and effective at capacity output can be undermined by demand failure.
Miller, Marcus, Zhang, Lei
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source