Results 41 to 50 of about 174,602,004 (288)

Conjugate Heat Transfer Study at Interior Surface of NGV Leading Edge with Combined Shower Head and Impingement Cooling

International Journal of Rotating Machinery, 2014
A computational study on conjugate heat transfer is carried out to present the behavior of nondimensional temperature and heat transfer coefficient of a Nozzle Guide Vane (NGV) leading edge.
Arun Kumar Pujari, B. V. S. S. S. Prasad, N. Sitaram   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Optimization direction and selection strategy for thin film thermoelectric cooler materials

Case Studies in Thermal Engineering
While thin-film thermoelectric coolers (TECs) are promising for chip thermal management, their material optimization strategy remains controversial. Conventional approaches focus on improving the material's figure of merit (ZT) by enhancing the power ...
Leyao Chu, Bingxuan Niu, Changbo Bu, Xiaolin Liang, Huazhong Zhang, Zhichun Liu, Yubo Tan, Limei Shen, Yongjun Sun   +8 more
doaj   +1 more source

Heat flux in a vibrated granular gas: the diffusive heat conductivity coefficient [PDF]

AIP Conference Proceedings, 2005
Ministerio de Ciencia y Tecnología (MCYT).
Brey Abalo, José Javier, Ruiz Montero, María José   +1 more
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Thermal Conductivity of Carbon Nanotubes and their Polymer Nanocomposites: A Review [PDF]

, 2011
Thermally conductive polymer composites offer new possibilities for replacing metal parts in several applications, including power electronics, electric motors and generators, heat exchangers, etc., thanks to the polymer advantages such as light weight ...
Fina, Alberto, Han, Zhidong, Zhidong Han, Alberto Fina   +3 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Evaluation of Fin Efficiency and Heat Transfer Coefficient for Fined Tube Heat Exchange [PDF]

, 2012
This study discussed the estimation of the fin efficiency and the pure-heat transfer coefficient in the heat exchanger. One hundred twenty cases of plate fins having known heat transfer coefficients were tested numerically to investigate the validity of ...
Kang, Hiechan
core