Results 91 to 100 of about 203,738,243 (304)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Nonlinear Aspects of Heat Pump Utilization
Acta Polytechnica, 2010 This work attempts to answer the question: How much can we believe that the coefficient of performance provided by the manufacturer is correct, when a heat pump is required to face the real load coming from changes of temperature?
R. Najman
doaj
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Frontiers in Mechanical EngineeringEffective thermal management of lithium-ion battery packs remains a critical challenge for ensuring the safety, performance, and longevity of Electric Vehicles (EVs) and Hybrid Electric Vehicles (HEVs).
Rallabandi Siva Krishnam Raju +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Optimization of the operation mode of a simple two-step heat pump with a separator
Известия высших учебных заведений: Проблемы энергетикиThe RELEVANCE of the research lies in the development of new methods for organizing the removal of low-potential heat from data centers, power electronics and other natural and technological sources, as well as in obtaining new dependencies for assessing
M. S. Purdin, V. V. Yuzyuk
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Performance Music: Virtual String Rehearsal
, 2020 University of Scranton Performance Music Instagram post regarding a virtual string ...
University of Scranton. Department of Performance Music
core +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Novel Glue-Stabilized Sorbent Layers for Adsorption Chillers: Thermal and Sorption Characteristics
EnergiesAdsorption chillers can produce chilled and desalinated water using low-grade heat, but their performance is limited by low coefficient of performance (COP) and large system mass.
Tomasz Bujok +6 more
doaj +1 more source