Results 141 to 150 of about 5,587 (151)

COELENTERAZINE-DEPENDENT LUCIFERASES: PROPERTIES AND APPLICATION

Lomonosov chemistry journal
The review presents data on the structure of bioluminescent systems of marine animals that use coelenterazine-dependent luciferases as light-emitting proteins. It has been shown that due to the availability, stability and high quantum yield of reactions, these luciferases, as well as their genetic variants with new useful properties, are successfully ...
L.A. FRANK, V.V. KRASITSKAYA
openaire   +1 more source

Synthetic Coelenterazine Derivatives and Their Application for Bioluminescence Imaging

2022
Bioluminescence (BL), the emission light resulting from the enzyme-catalyzed oxidative reaction, is a powerful imaging modality for monitoring biological phenomena both in vitro and in vivo. Coelenterazine (CTZ), the known widespread luciferin found in bioluminescent organisms, develops bioluminescence imaging (BLI).
Tianyu, Jiang, Minyong, Li
openaire   +2 more sources

Efficient synthesis and antioxidant activity of coelenterazine analogues

Tetrahedron Letters, 2014
Abstract A convenient and highly convergent method for the synthesis of new imidazo[1,2- a ]pyridine-based coelenterazine analogues is reported. The imidazo[1,2- a ]pyridine core was constructed through a condensation between 2-aminopyridine analogues and arylglyoxals.
Lu, Yueting, Hendra, Rudi, Oakley, Aaron J, Keller, Paul A   +3 more
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Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution

Chemical Communications, 2015
Coelenterazine derivatives with extended substituents show significant bioluminescence emission with knownrenillaluciferase variants, indicating a promising method to develop substrates with superior optical properties.
Ryo, Nishihara, Hideyuki, Suzuki, Emi, Hoshino, Sakura, Suganuma, Moritoshi, Sato, Tsuyoshi, Saitoh, Shigeru, Nishiyama, Naoko, Iwasawa, Daniel, Citterio, Koji, Suzuki   +9 more
openaire   +2 more sources

Widespread occurrence of coelenterazine in marine bioluminescence

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1980
Abstract 1. 1. Coelenterazine is a compound having a key role in the light-emitting process of bioluminescent coelenterates. Present evidence concerning the occurrence of coelenterazine and luciferase in other types of marine organisms establishes that coelenterazine is required for bioluminescence of various, distantly related, types of ...
Osamu Shimomura, Shoji Inoue, Frank H Johnson, Yata Haneda   +3 more
openaire   +1 more source

Antioxidative properties of natural coelenterazine and synthetic methyl coelenterazine in rat hepatocytes subjected to tert-butyl hydroperoxide-induced oxidative stress

Biochemical Pharmacology, 2000
Coelenterazine (CLZn; 3, 7-dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo++ +[1 ,2-a]pyrazin-3-one), the substrate for bioluminescence reactions in many marine animals, is endowed with high antioxidant properties. This work investigated the antioxidative properties of CLZn in primary cultures of rat hepatocytes subjected to the ...
M L, Dubuisson, B, de Wergifosse, A, Trouet, F, Baguet, J, Marchand-Brynaert, J F, Rees   +5 more
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Synthesis of Coelenterazine

Analytical Biochemistry, 1996
G, Gonzalez-Trueba, C, Paradisi, M, Zoratti   +2 more
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COELENTERAZINE DERIVATIVES FOR IMPROVED SOLUTION SOLUBILITY

Bioluminescence and Chemiluminescence, 2002
ERIKA M. HAWKINS, MICHAEL O'GRADY, DIETER KLAUBERT, MICHAEL SCURRIA, TROY GOOD, CATHY STRATFORD, ROD FLEMMING, DAN SIMPSON, KEITH V. WOOD   +8 more
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The Coelenterazines

2012
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THE COELENTERAZINES

2006
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