Results 61 to 70 of about 38,269 (258)

Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo [PDF]

, 2019
Detoxification of gluten immunogenic epitopes is a promising strategy for the treatment of celiac disease. Our previous studies have shown that these epitopes can be degraded in vitro by subtilisin enzymes derived from Rothia mucilaginosa, a natural ...
Darwish, Ghassan, Helmerhorst, Eva J., Oppenheim, Frank G., Schuppan, Detlef, Wei, Guoxian   +4 more
core   +1 more source

Factors associated with diagnostic and treatment intervals in colorectal cancer: A linked data study

International Journal of Cancer, EarlyView.
What's New? Colorectal cancer (CRC) is often diagnosed not by screening but because symptoms occur. Previous studies investigating the length of time between presentation and diagnosis have focused on patient characteristics, but here, the authors also look at how provider and health system factors contribute to longer diagnostic intervals, using an ...
Allison Drosdowsky, Karen E. Lamb, Luc te Marvelde, Peter Gibbs, Catherine Dunn, Ian Faragher, Ian Jones, Maarten J. IJzerman, Jon D. Emery   +8 more
wiley   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, EarlyView.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Antegrade coeliac axis reconstruction for Chronic Mesenteric Ischaemia : a case series [PDF]

, 2009
The management of chronic mesenteric ischaemia remains a compelling challenge for many vascular surgeons. Over the past four decades, several reports have demonstrated encouraging results following revascularisation of the splanchnic arteries.
Allaf, Nile, Gingell Littlejohn, Marc, Tait, William F., Walford, Lara   +3 more
core  

Long-term care for patients with coeliac disease in the UK: a review of the literature and future directions. [PDF]

, 2016
Coeliac disease is a common digestive disorder that affects 1% of adults. It is characterised by mucosal damage of the small intestine caused by dietary gluten.
Bardella, Bebb, Biagi, Biagi, Canavan, Ciacci, Ciacci, Comino, Cooper, Dewar, Fera, Galli, Gray, Haines, Hall, Heel, Holmes, Ilus, Irvine, Kang, Kurppa, Lebwohl, Lee, Leffler, Leffler, Lohi, Lohi, Ludvigsson, Mahadev, Mangione RA, Metzger, Mooney, Moreno, Mulder, Murray, Nazareth, Norstrom, Rubio-Tapia, Rubio-Tapia, Sainsbury, Sainsbury, Sharkey, Silano, Silvester, Tau, Tennyson, Thanvi, West, West   +48 more
core   +1 more source

Using Photovoice Methods to Set Research Priorities With Autistic People With Experience of an Eating Disorder

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objective(s) Autism and Autistic traits are heightened in individuals with eating disorders (EDs), with Autistic people reporting poorer treatment outcomes and experiences. Despite this, mechanisms of this overlap remain poorly understood, perhaps due to an exclusion of lived experience perspectives in setting research agendas.
Emy Nimbley, Kyle Buchan, Ellen Maloney, Sarah Kettley, Michelle Sader, Fiona Duffy, Karri Gillespie‐Smith   +6 more
wiley   +1 more source

Letter: Supporting the Role of Enzyme Therapy in Management of Coeliac Disease-Authors' Reply. [PDF]

Aliment Pharmacol Ther
Alimentary Pharmacology &Therapeutics, Volume 62, Issue 1, Page 103-104, July 2025.
Bonner ER, Tschollar W, Anderson R, Mourabit S.   +3 more
europepmc   +2 more sources

Celiac disease [PDF]

, 2006
Celiac disease is a chronic intestinal disease caused by intolerance to gluten. It is characterized by immune-mediated enteropathy, associated with maldigestion and malabsorption of most nutrients and vitamins.
Caspary, Wolfgang F., Holtmeier, Wolfgang   +1 more
core  

Quantification of gliadin levels to the picogram level by flow cytometry [PDF]

, 2005
Celiac disease is a widely prevalent enteropathy caused by intolerance to gliadin, one of the gluten proteins. We developed two methods for the analysis of gliadin levels. Both methods use flow cytometry and rat antibodies against a 16-residue peptide of
CAPPARELLI R, IANNELLI D., LONGOBARDO, LUIGI, VENTIMIGLIA L   +3 more
core   +1 more source

Comparable impact of lymph node metastases in T2 gallbladder cancer on postoperative prognosis irrespective of the extent of the metastases: A retrospective analysis

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background Lymph node metastases beyond the hepatoduodenal ligament are sometimes encountered in locally limited T2 gallbladder cancer (GBCA). However, the incidence and impact on prognosis remain unclear. Methods This was a retrospective multi‐institutional study of patients who underwent surgical resection for GBCA from 2002 to 2022.
Yoji Kishi, Teiichi Sugiura, Takashi Mizuno, Hiromichi Ito, Yu Takahashi, Takehiro Noji, Yuta Abe, Shimpei Otsuka, Shoji Kawakatsu, Asayo Kato, Masayuki Tanaka, Tomoki Ebata, Satoshi Hirano   +12 more
wiley   +1 more source