Results 131 to 140 of about 166,204 (247)

Phosphonomethyl (Thio)Phosphonamidite Reagents for the Construction of Phosphonylmethyl Phosphono(Di)Thioate Mono‐ and Diesters

open access: yesChemistry – A European Journal, EarlyView.
A set of new phosphonomethyl (thio)phosphonamidite reagents is introduced to generate unprecedented pyrophosphate mimetics. The versatile P(III)‐P(V) reagents allow for the construction of various pyrophosphate isosteres, and the applicability of the chemistry is illustrated in the assembly of a diverse set of stabilized CDP‐glycerol and CDP‐ribitol ...
Pascal Balić   +4 more
wiley   +1 more source

Thiamine Diphosphate‐Dependent Biocatalysis in the 21st Century

open access: yesChemistry – A European Journal, EarlyView.
This account summarizes the major discoveries and recent advances, highlighting the biocatalytic abilities, mechanistic studies, and feature‐based classification that are shaping emerging perspectives on thiamine diphosphate (ThDP)‐dependent catalysis.
Lucrezia Lanza   +2 more
wiley   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung   +12 more
wiley   +1 more source

Harnessing Natural Wood Architecture: A Self‐Supporting, Hierarchically Porous NiFe@Carbon Capacitive Anode Enhances Electricity Generation and Storage in Microbial Fuel Cells

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study reports a mild “Zn(NO3)2 interlayer‐expansion” strategy combined with electrodeposition to produce a self‐supporting capacitive anode (NiFe@PC) that preserves the wood's native low‐tortuosity channels. The retained native architecture expands niches for microbial colonization.
Xue Liu   +10 more
wiley   +1 more source

Coenzyme Q10 production from marine bacteria

open access: yes, 2010
Disclosed are methods, compounds and compositions related to the production of coenzyme
A Burja (13752124)   +2 more
core  

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

COQ8 chaperones coenzyme Q lipid intermediates through ATP-driven structural gating. [PDF]

open access: yesSci Adv
Gottinger A   +16 more
europepmc   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Statin use and risk of remote seizure after first new onset status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Preclinical evidence supports the role of statins as antiepileptogenic agents. In this study, we investigated the risk of remote unprovoked seizures (RS) according to the use of statin therapy in a cohort of first‐ever status epilepticus (SE) survivors. Methods Retrospective analysis was made of adult patients (age ≥ 14 years) with a
Niccolò Orlandi   +12 more
wiley   +1 more source

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