Results 331 to 340 of about 25,277,741 (360)

Genetic analyses of very long-chain acyl-coenzyme A dehydrogenase deficiency: A case report with a novel ACADVL variant. [PDF]

Mol Genet Metab Rep
Zhou W, Li H, Yang L.
europepmc   +1 more source

Salidroside Improves Oocyte Competence of Reproductively Old Mice by Enhancing Mitophagy

Aging Cell, EarlyView.
Salidroside improves oocyte competence by enhancing mitophagy. Aging impairs mitophagy in oocytes, which leads to mitochondrial dysfunction. Salidroside restores mitochondrial homeostasis, reduces ROS levels, and improves oocyte developmental competence.
Jingkai Gu, Renwu Hua, Huayan Wu, Chenxi Guo, Zhuo Hai, Yuan Xiao, William S. B. Yeung, Kui Liu, Elnur Babayev, Tianren Wang   +9 more
wiley   +1 more source

The Spectrum of clinical manifestations in newborns with the COQ4 mutation: case series and literature review. [PDF]

Front Pediatr
Pan P, Zhou N, Sun Y, Chen Z, Han J, Zhou W.   +5 more
europepmc   +1 more source

Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures

Aging Cell, EarlyView.
Longevity humans have “a youthful erythrocyte function and metabolism” with a youth‐like oxygen release and anti‐oxidative capability to combat tissue hypoxia and improve healthspan. ABSTRACT Longevity individuals have lower susceptibility to chronic hypoxia, inflammation, oxidative stress, and aging‐related diseases.
Fang Yu, Changhan Chen, Wuping Liu, Zhixiang Zhao, Yuhua Fan, Zhenjiang Li, Weilun Huang, Tingting Xie, Cheng Luo, Zhouzhou Yao, Qi Guo, Zhiyu Yang, Juan Liu, Yujin Zhang, Rodney E. Kellems, Jian Xia, Ji Li, Yang Xia   +17 more
wiley   +1 more source

Efficacy Evaluation of "Enhanced" Natural Killers with <i>CISH</i> and <i>B2M</i> Knockouts on Viability and Metabolic Status of 3D Glioblastoma Spheroid Cells in Patients. [PDF]

Sovrem Tekhnologii Med
Yuzhakova DV, Sachkova DA, Shirmanova MV, Shcheslavskiy VI, Mozherov AM, Dashinimaev EB, Baklaushev VP, Yusubalieva GM.   +7 more
europepmc   +1 more source

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt‐Dependent NAD+ De Novo Synthesis in Mice

Aging Cell, EarlyView.
In Qprt‐deficient mice, testicular NAD+ levels decline accelerated with age, leading to mitochondrial dysfunction, disrupted DSB repair, impaired meiotic sex chromosome inactivation, and germ cell loss. Nicotinamide riboside (NR) supplementation restores NAD+ levels and alleviates these defects, highlighting the importance of NAD+ de novo synthesis in ...
Yining Xu, Huan Wang, Hui Li, Chenlu Wei, Zhenye Zhu, Yanqing Zhao, Jiajia Zhu, Min Lei, Yingpu Sun, Qingling Yang   +9 more
wiley   +1 more source

Maize 4-coumarate coenzyme A ligase Zm4CL-like9 gene positively regulates drought stress response in Arabidopsis thaliana. [PDF]

GM Crops Food
Fan J, Luo Z, Wang Y, Jiao P, Wang Q, Dai Y, Guan S, Ma Y, Yu H, Liu S.   +9 more
europepmc   +1 more source

Pyrroloquinoline Quinone Reprograms the Single‐Cell Landscape of Immune Aging in Hematopoietic Immune System

Aging Cell, EarlyView.
This study demonstrates that aging induces oxidative stress and inflammation in the hematopoietic immune system, resulting in immune homeostasis dysfunction, including alterations in B cells and hematopoietic stem cells, senescent cells (SnCs) accumulation, and senescence‐associated secretory phenotypes (SASPs) production. Notably, the study highlights
Xiuxing Liu, Chun Zhang, Jianjie Lv, Yidan Liu, Chenyang Gu, Yuehan Gao, Wen Ding, Hui Chen, Nanwei Xu, Hongbin Yin, Wenru Su, Zhuping Xu   +11 more
wiley   +1 more source

Cometabolism of ferrihydrite reduction and methyl-dismutating methanogenesis by <i>Methanosarcina mazei</i>. [PDF]

Appl Environ Microbiol
Guo C, Lu Y.
europepmc   +1 more source

From Monotherapy to Adjunctive Therapies: Application of Dermocosmetics in Acne Management Across Australia and New Zealand

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Acne vulgaris is a globally prevalent dermatological disease, with its severity ranging from mild to severe. While moderate to severe acne often requires topical or systemic pharmaceutical therapy, mild to moderate acne may be managed with dermocosmetics, which are over‐the‐counter skincare agents with active ingredients that target acne ...
Ryan De Cruz, Rebecca Nguyen, Peggy Chen, Delphine Kerob, Kurt Gebauer, Anneliese Willems, Philip Tong, Michael Lee   +7 more
wiley   +1 more source