Results 151 to 160 of about 96,183 (271)

Coenzyme Q10 in the Human Retina

Investigative Opthalmology & Visual Science, 2009
To determine the concentration of coenzyme Q10 (CoQ10) in the human retina.Eye tissues were lyophilized and exhaustively extracted with heptane. The extracts were analyzed for CoQ10 by high-performance liquid chromatography (HPLC).The average concentration of CoQ10 in the retina was 42+/-11 nanomoles/g dry retina for donors younger than 30 years of age
Jinfeng, Qu, Yardana, Kaufman, Ilyas, Washington   +2 more
openaire   +2 more sources

Uncovering Coenzyme Q10‐Related Genetic Determinants of Statin‐Associated Muscle Symptoms: Evidence from the UK Biobank and the All of Us Research Program

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 475-483, August 2026.
Statin‐associated muscle symptoms (SAMS) are frequent adverse effects of statin therapy and have been hypothesized to result from impaired coenzyme Q10 (CoQ10) biosynthesis. Although genetic determinants of CoQ10 levels have been reported, genome‐wide association studies (GWASs) conducted specifically in statin users are lacking. Moreover, direct CoQ10
Da Hoon Lee, Yoon‐A Park, Yubin Song, Ji‐Min Han, Kyung Hee Choi, Myeong Gyu Kim, Hye Sun Gwak   +6 more
wiley   +1 more source

Atorvastatin therapy and antioxidant status correction in patients with metabolic syndrome

Российский кардиологический журнал, 2013
Aim. To study the changes in antioxidant status and glucose-insulin homeostasis among atorvastatin-treated patients with metabolic syndrome and to investigate the potential of coenzyme Q10 for the correction of these changes. Material and methods.
N. S. Yubitskaya, M. V. Antonyuk, V. I. Yankova   +2 more
doaj   +1 more source

Metformin Partially Attenuates Simvastatin‐Induced Myotoxic Responses in C2C12 Myotubes Through Metabolic Adaptation

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Simvastatin induces metabolic suppression, mitochondrial dysfunction, and atrophy‐related responses in skeletal muscle cells. In differentiated C2C12 myotubes, metformin partially attenuates these alterations by preserving myotube structural integrity, reducing cellular stress signaling, and maintaining mitochondrial network organization despite ...
Chuqi He, Mike Wesselink, Jelle Y. Huijts, Zhenjia Zhong, Moritz Eggelbusch, Richard T. Jaspers, Rob C. I. Wüst   +6 more
wiley   +1 more source

Impact of Biologic and Conventical Synthetic DMARDs on Serum Coenzyme Q10 and Malondialdehyde in Rheumatoid Arthritis Patients

مجلة كلية الطب
Background: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune illness. Oxidative stress such as Malondialdehyde plays a major role in the pathophysiology of RA while antioxidants such as Coenzyme Q10 play protect role against inflammation.
Nagham Y. Mohsin, Basil O. Saleh, Faiq I. Gorial   +2 more
doaj   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy, Sally Smith, Marita Smith, Catherine Atthow, Janette Spicer, Matthew Lynch, Michelle Lipke, Julie A. McEniery, David Coman, Anita Inwood, Jim McGill, Carolyn Bursle   +11 more
wiley   +1 more source

Coenzyme Q10 Supplementation for the Treatment of Statin Induced Myalgia [PDF]

, 2010
Background: A significant number of the population is on 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) because statins are the main pharmacologic drug prescribed for the treatment of hypercholesteremia.
Asherin, Jessica P.
core   +1 more source

Coenzyme Q10 fetal plasma levels [PDF]

, 1998
This study aims at determining a cutoff value differentiating the fetal from the adult coenzyme Q10 (CoQ10) values and comparing substantial increases in CoQ10 plasma levels in fetuses with hypoxic hypoxia and nonimmune fetal ...
Mancuso, Salvatore, De Santis, Marco, Caruso, Alessandro, Noia, Giuseppe   +3 more
core  

“Coenzyme Q10” (Coenzym Q10) [PDF]

IIC - International Review of Intellectual Property and Competition Law, 2016
openaire   +1 more source

Coenzyme Q4 is a functional substitute for coenzyme Q10 and can be targeted to the mitochondria [PDF]

Coenzyme Q10 ...
Sung, Andrew Y, Rogers, Sean, Steenberge, Laura H, Pagliarini, David J, Fan, Jing   +4 more
core   +2 more sources