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Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations

Mitochondrion, 2007
Plasma coenzyme Q10 (CoQ10) response to oral ingestion of various CoQ10 formulations was examined. Both total plasma CoQ10 and net increase over baseline CoQ10 concentrations show a gradual increase with increasing doses of CoQ10. Plasma CoQ10 concentrations plateau at a dose of 2400 mg using one specific chewable tablet formulation.
Raj K Chopra
exaly   +3 more sources

Lipid nanoparticles containing coenzyme Q10 for topical applications: An overview of their characterization.

Colloids and Surfaces B: Biointerfaces, 2023
The coenzyme Q10 is a compound widely used in pharmaceutical and cosmetic formulations because it is a potent eliminator of free radicals, giving it antioxidant and anti-aging properties.
I. D. L. Souza, V. Saez, C. Mansur
semanticscholar   +1 more source

Influence of Pore Size and Surface Functionalization of Mesoporous Silica Nanoparticles on the Solubility and Antioxidant Activity of Confined Coenzyme Q10.

Molecular Pharmaceutics, 2023
Coenzyme Q10 is a potent antioxidant that plays an important role in the maintenance of various biochemical pathways of the body and has a wide range of therapeutic applications. However, it has low aqueous solubility and oral bioavailability. Mesoporous
A. Meka   +11 more
semanticscholar   +1 more source

In vitro bioaccessibility of coenzyme Q10 in enriched yoghurts [PDF]

open access: yesInternational Journal of Food Science and Technology, 2012
In this study, the aim was to determine the bioaccessibilities of coenzyme Q10 (CoQ10) in yoghurt samples produced using enriched skim milk with different coenzyme Q10 preparations.
Sedef Nehir El
exaly   +2 more sources

The influence of dietary coenzyme Q10 and vitamin C on the growth rate, immunity, oxidative-related genes, and the resistance against Streptococcus agalactiae of Nile tilapia (Oreochromis niloticus)

Aquaculture, 2021
Dietary coenzyme Q10 (CoQ10) and vitamin C (Vc) are natural immunostimulants and antioxidants involved in improving the performances and health conditions of aquatic animals.
M. F. El Basuini   +8 more
semanticscholar   +1 more source

Coenzyme Q10 in Pregnancy

Fetal Diagnosis and Therapy, 2009
Our objectives were to assess the plasma coenzyme Q10 (CoQ10) levels in normal pregnancy, in pregnancy with a spontaneous contractile event, in spontaneous abortion and in threatened abortion. Six hundred and fifteen CoQ10 levels were analyzed in 483 pregnant women: 350 patients were employed to design a normal curve; 66 patients with spontaneous ...
Noia, Giuseppe   +6 more
openaire   +3 more sources

Pharmacokinetics of coenzyme Q10

Bulletin of Experimental Biology and Medicine, 2008
The pharmacokinetics of coenzyme Q10 powder and solution of solubilized form was studied after their oral administration to rats (10 mg/kg). Plasma concentrations of coenzyme Q10 were measured by HPLC with electrochemical detection over 48 hours. Solubilized coenzyme Q10 exhibited high absorption creating higher plasma concentrations of the drug, as a ...
E I, Kalenikova   +2 more
openaire   +2 more sources

Coenzyme Q10. [PDF]

open access: yesAmerican family physician, 2005
Coenzyme Q10 is a vitamin-like substance used in the treatment of a variety of disorders primarily related to suboptimal cellular energy metabolism and oxidative injury. Studies supporting the efficacy of coenzyme Q10 appear most promising for neurodegenerative disorders such as Parkinson's disease and certain encephalomyopathies for which coenzyme Q10
Robert Alan, Bonakdar, Erminia, Guarneri
openaire   +2 more sources

Coenzyme Q10 in aging and disease

Critical reviews in food science and nutrition, 2022
Coenzyme Q10 (CoQ10) is an essential component of the electron transport chain. It also acts as an antioxidant in cellular membranes. It can be endogenously produced in all cells by a specialized mitochondrial pathway.
Amin Gasmi   +5 more
semanticscholar   +1 more source

Chlorogenic acid, quercetin, coenzyme Q10 and silymarin modulate Keap1-Nrf2/heme oxygenase-1 signaling in thioacetamide-induced acute liver toxicity.

Life Science, 2021
BACKGROUND AND AIMS The normal functioning of Kelch-like ECH-associated protein-1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2) complex is necessary for the cellular protection against oxidative stress.
Rasha M. Hussein   +3 more
semanticscholar   +1 more source

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