Results 101 to 110 of about 419,459 (324)
Application of cell-free translation systems to studies of cofactor binding proteins [PDF]
, 2004 Masato Abe
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, 2014 Citation: 'cofactors' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01128 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Advanced Synthesis &Catalysis, EarlyView.We show how engineered ancestral amide bond synthetases (ABSs) together with cofactor recycling using a single polyphosphate kinase paves the way for chemoenzymatic synthesis of pharmacophores. The figure illustrates how ancestral ABS has a more flexible C‐terminal domain, which is associated with enhanced catalytic performance and expanded amine scope.
Elisabeth Söderberg +5 more
wiley +1 more source
Biosynthesis of ethylene. Methanesulphinic acid as cofactor in the enzymic formation of ethylene from methional [PDF]
, 1969 L. W. Mapson, R. Self, D. A. Wardale
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Flavin Biosynthesis Enhances Extracellular Electron Transfer in Bioengineered Escherichia coli
Advanced Science, EarlyView.Microbial electronics are promising for energy, sensing, environmental, and synthesis applications. E. coli are engineered with extracellular electron transfer (EET) pathways from a microbe that naturally produces current to enable bioelectronics based on E. coli.
Mohammed Mouhib +4 more
wiley +1 more source
Taylor Expansion Proof of the Matrix Tree Theorem - Part I
, 2013 The Matrix-Tree Theorem states that the number of spanning trees of a graph is given by the absolute value of any cofactor of the Laplacian matrix of the graph.
Zernik, Amitai
core
Improving the Enzymatic Cascade of Reactions for the Reduction of CO2 to CH3OH in Water: From Enzymes Immobilization Strategies to Cofactor Regeneration and Cofactor Suppression [PDF]
, 2022 Carmela Di Spiridione +2 more
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Advanced Science, EarlyView.Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
Advanced Science, EarlyView.NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
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Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Advanced Science, EarlyView.Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
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