Results 181 to 190 of about 419,459 (324)

Not only an inhibitor: Trehalose enhances the catalytic action exerted on oxaloacetate by rabbit lactate dehydrogenase. [PDF]

Protein Sci
Stefan A, Hochkoeppler A.
europepmc   +1 more source

BRIGHT Enables High‐SNR Live‐Cell Imaging of Non‐Repetitive Sequences via Bivalent Fluorescent Nanobody‐Mediated Cascade‐Dependent Illumination

Advanced Science, EarlyView.
BRIGHT is a newly developed live‐cell imaging system that integrates cascade amplification with background denoising through the bivalent binding capability and antigen‐dependent stability of a bivalent fluorescent nanobody targeting ALFA peptides.
Lei Feng, Tao Huang, Yanxi Han, Meng Tian, Duo Wang, Zilong Mei, Yu Ma, Yingshuo Ma, Jinming Li, Rui Zhang   +9 more
wiley   +1 more source

Cell-Free-Based Thermophilic Biocatalyst for the Synthesis of Amino Acids from One-Carbon Feedstocks. [PDF]

ACS Synth Biol
Westenberg R, Chowdhury S, Cardiff R, Wennerholm K, Beliaev AS, Carothers JM, Peralta-Yahya P.   +6 more
europepmc   +1 more source

Regioselective Hydration of Terpenes with Cofactor‐Independent Carotenoid 1,2‐Hydratase

Philip Horz, Natalie Härterich, Andreas Schneider, Nicolas D. Travnicek, Bettina M. Nestl, Ursula Kahler, Bernhard Hauer   +6 more
openalex   +1 more source

Shear Stress–Dependent Regulation of the Human β-Tubulin Folding Cofactor D Gene [PDF]

, 2000
Andreas Schubert, Marco Cattaruzza, Markus Hecker, Dorothea Darmer, Juergen Holtz, Henning Morawietz   +5 more
openalex   +1 more source

A Dynamic Gate Enables Regioselective Hydroxylation of Free Arginine by a Non‐Canonical Heme Enzyme

Advanced Science, EarlyView.
The YqcI/YcgG enzyme AglA employs a unique “sandwich” fold and a dynamic gating mechanism to selectively hydroxylate AMPn‐Arg at Nε. Site‐directed mutations reprogram regioselectivity or enable activity on free arginine by altering hydrogen‐bond networks, precisely positioning substrates.
Yuan Sun, Chao Dou, Weizhu Yan, Pengpeng Chen, Lu Zhang, Dan Zhou, Yanhui Zheng, Zhaolin Long, Shoujie Li, Xiaoqing Xu, Qiuxia Huang, Xiaofeng Zhu, Wei Cheng   +12 more
wiley   +1 more source

Crystal structure of MutYX: a novel clusterless adenine DNA glycosylase with a distinct C-terminal domain and 8-oxoguanine recognition sphere. [PDF]

Nucleic Acids Res
Trasviña-Arenas CH, Hashemian M, Malek M, Merrill S, Fisher AJ, David SS.   +5 more
europepmc   +1 more source

SRF and SRF Cofactor mRNA Expression Is Differentially Regulated by BDNF Stimulation in Cortical Neurons

, 2023
Daisuke Ihara, Tomoaki Miyata, Mamoru Fukuchi, Masaaki Tsuda, Akiko Tabuchi   +4 more
openalex   +2 more sources

An Efficient CO2‐Upcycling Platform Based on Engineered Halomonas TD with Enhanced Acetate‐Utilizing Capacity via Adaptive Laboratory Evolution

Advanced Science, EarlyView.
An electrochemical system is designed to convert CO2 into CO2‐derived electrolytes (CDE), mainly containing acetate and formate. The underlying mechanism of acetate metabolism in Halomonas TD80 is explored via ALE. Engineered TD80 produced high‐yield diversified products from CDE.
Chi Wang, Ting‐Ting Chen, Yu‐Jiao Yang, Yu‐Xi Li, Yi‐Xin Chang, Yan‐Chun Xiao, Wen‐Tai Guo, Ye Zheng, Rui‐Zhe Deng, Yu‐Xiang Tian, Wei Situ, Hong‐Wei Shen, Yu Chen, Ya‐Bin Wang, Jie Xing, Hui Wang, Lin Xia, Yi‐Na Lin, Jian‐Wen Ye   +18 more
wiley   +1 more source

Prediction of UGT-mediated phase II metabolism via ligand- and structure-based predictive models. [PDF]

J Cheminform
Bono L, Lunghini F, Sabato E, Biswas AD, Mazzolari A, Pedretti A, Beccari AR, Vistoli G, Vittorio S.   +8 more
europepmc   +1 more source