Results 201 to 210 of about 221,534 (298)

Structural dynamics of the π-stacking network governing cofactor-substrate cooperativity of SbSOMT methyltransferase. [PDF]

Commun Chem
Pow KC, Zhang N, Yan M, Wang X, Lui ACW, Lo C, Hao Q.   +6 more
europepmc   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to <i>p</i>-aminobenzenesulfonamide. [PDF]

Front Bioeng Biotechnol
Ai R, Muhammad N, Cui Y, Wang L, Wang Y, Weng S, Kakar MU, Khan S, Ahmad S.   +8 more
europepmc   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Discovery and characterization of a nickel enzyme family that catalyses intermolecular hydride shuttling. [PDF]

Nat Chem
Semersky ZL, Raymond CG, Rossi JM, Hofstetter H, Rao P, Neugebauer ME.   +5 more
europepmc   +1 more source

Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis

Advanced Science, EarlyView.
Conjugated polymer‐supported bioelectrochemical systems are shown to enhance microbial electrosynthesis by triggering coordinated electrochemical, transcriptional, post‐transcriptional (sRNA), metabolic, and protein‐level responses. Integrated multi‐omics and electrochemical analyses reveal selective physiological remodeling associated with improved ...
David Ohayon, Yuanmei Liang, Zexuan Wang, Jee Loon Foo, Glenn Quek, Samantha R. McCuskey, Zhongxin Chen, Matthew Wook Chang, Guillermo C. Bazan   +8 more
wiley   +1 more source

Influence of heme and pH on the oligomeric states of Brucella melitensis bacterioferritin. [PDF]

Acta Crystallogr D Struct Biol
Scaillet T, Champagne C, Wouters J.
europepmc   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

Catalytic Properties of NADP-Reducing Enzymes from <i>Streptococcus cristatus</i> ATCC 51100. [PDF]

Biomolecules
Schütt I, Teuffel J, Hlawatschke BH, Einwohlt P, Kreikemeyer B, Wade RC, Fiedler T.   +6 more
europepmc   +1 more source