Results 1 to 10 of about 133,360 (260)
Physiological metabolic analysis and process optimization of hypoxia in promoting coenzyme Q10 biosynthesis and accumulation in Rhodobacter sphaeroides HY01 [PDF]
Synthetic and Systems BiotechnologyCoenzyme Q10 fermentation by Rhodobacter sphaeroides (R. sphaeroides) is highly aerobic. However, its biosynthesis and accumulation are paradoxically induced under hypoxic conditions.
Bo Li +9 more
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Inhibition of Histone Lysine Acetyltransferases by Coenzyme A Analogs [PDF]
MoleculesHistone lysine acetylation is a widespread posttranslational modification, essential for vital functions in eukaryotic organisms. Histone lysine acetyltransferases (KATs) employ acetyl-coenzyme A as a universal acetyl donor for acetylation of lysine ...
Faidra Voukia +3 more
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Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review [PDF]
Journal of International Medical ResearchObjective This study aimed to investigate whether coenzyme Q10 is effective in preventing exercise-induced oxidative stress and muscle damage. Methods Fourteen randomized controlled studies examining the effects of supplementation with coenzyme Q10 ...
Yangqi Zhang +4 more
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mBio, 2022 In bacteria, many essential metabolic processes are controlled by riboswitches, gene regulatory RNAs that directly bind and detect metabolites. Highly specific effector binding enables riboswitches to respond to a single biologically relevant metabolite.
Kristopher J. Kennedy +6 more
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4,7-Dimethoxy-6-propyl-2H-1,3-benzodioxole-5-carbaldehyde
Molbank, 2023 A simple intermediate for the synthesis of methoxy-analogues of coenzymes Q with substituents having various chain lengths based on natural polyalkoxyallylbenzene apiol has been developed.
Dmitry V. Tsyganov, Victor V. Semenov
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Endocrine Regulations, 2021 Objectives. The present study was designed to assess whether apoptosis-related genes as parp-1 and bax could be targets for treatment of diabetes mellitus and whether vitamin D may exert beneficial effects.
Kuchmerovska Tamara +5 more
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Metabolites, 2022 Hypoxia poses a major physiological challenge for mammals and has significant impacts on cellular and systemic metabolism. As with many other small rodents, naked mole-rats (NMRs; Heterocephalus glaber), who are among the most hypoxia-tolerant mammals ...
Hang Cheng +5 more
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Structural Basis for Allostery in PLP-dependent Enzymes
Frontiers in Molecular Biosciences, 2022 Pyridoxal 5′-phosphate (PLP)-dependent enzymes are found ubiquitously in nature and are involved in a variety of biological pathways, from natural product synthesis to amino acid and glucose metabolism.
Jenny U. Tran +2 more
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Journal of Biological Chemistry, 2005 Iso-coenzyme A is an isomer of coenzyme A in which the monophosphate is attached to the 2'-carbon of the ribose ring. Although iso-CoA was first reported in 1959 (Moffatt, J. G., and Khorana, H. G. (1959) J. Am. Chem. Soc. 81, 1265-1265) to be a by-product of the chemical synthesis of CoA, relatively little attention has been focused on iso-CoA or on ...
Kristi L, Burns +4 more
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mBio, 2022 Coenzyme F420 is a microbial redox cofactor that mediates diverse physiological functions and is increasingly used for biocatalytic applications. Recently, diversified biosynthetic routes to F420 and the discovery of a derivative, 3PG-F420, were reported.
Mahmudul Hasan +8 more
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