Results 21 to 30 of about 166,204 (247)
Frontiers in Microbiology, 2018 Oxidoreductases are ubiquitous enzymes that catalyze an extensive range of chemical reactions with great specificity, efficiency, and selectivity. Most oxidoreductases are nicotinamide cofactor-dependent enzymes with a strong preference for NADP or NAD ...
Andrea M. Chánique +2 more
doaj +1 more source
Analysis and Suggestions of Evaluation and Approval for Health Foods Containing Coenzyme Q10
Shipin gongye ke-ji, 2022 Coenzyme Q10 is a fat-soluble vitamin-like benzoquinone compound, which is synthesized endogenously from tyrosine in human body. It has many physiological functions, such as participating in ATP production capacity, scavenging free radicals and anti ...
Yu JIANG +4 more
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A Convenient Two-Step Synthesis of Coenzyme Q1 [PDF]
, 2019 A convenient method for the preparation of Coenzyme Q1 from the cheap and readily available 3,4,5-Trimethoxytoluene was developed. CoQ1 was synthesized in moderate yield by a two-step procedure involving the key reaction of allyl bromide with CoQ0 ...
Wan-Yue, Luo +4 more
core +1 more source
Effect of iron and silver nanoparticles on coenzyme Q10 production by Gluconobacter japonicus FM10
Iranian Journal of Microbiology, 2020 Background and Objectives: Coenzyme Q10 is an anti-aging agent whose demand is increasing progressively. There are various strategies used for increasing coenzyme Q10 production by microorganisms.
Foozieh Moghadami, Ramin Hosseini
doaj +1 more source
Heart Failure—Do We Need New Drugs or Have Them Already? A Case of Coenzyme Q10
Journal of Cardiovascular Development and Disease, 2022 Heart failure (HF) is a global epidemic that contributes to the deterioration of quality of life and its shortening in 1–3% of adult people in the world. Pharmacotherapy of HF should rely on highly effective drugs that improve prognosis and prolong life.
Krzysztof J. Filipiak +3 more
doaj +1 more source
Thiamine antagonists trigger p53-dependent apoptosis in differentiated SH-SY5Y cells
Scientific Reports, 2017 Accumulating evidences suggest that p53 is a key coordinator of cellular events triggered by oxidative stress often associated with the impairment in thiamine metabolism and its functions.
Sergiy Chornyy +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Cyprus Journal of Medical SciencesBACKGROUND/AIMS: Testicular dysfunction has been reported in hypothyroidism. However, the effect of hypothyroidism on spermatogonial stem cells (SSCs) is not understood.
Hatice Nur Şeflek +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source