Results 41 to 50 of about 166,204 (247)

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou   +6 more
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks   +8 more
wiley   +1 more source

The phosphatase Ptc7 induces coenzyme Q biosynthesis by activating the hydroxylase coq7 in yeast

open access: yes, 2013
The study of the components of mitochondrial metabolism has potential benefits for health span and lifespan because the maintenance of efficient mitochondrial function and antioxidant capacity is associated with improved health and survival.
Padilla, Sergio   +6 more
core   +1 more source

Design, optimization and characterization of coenzyme Q10- and D-panthenyl triacetate-loaded liposomes [PDF]

open access: yes, 2017
Burak Çelik,1 Ali Asram Sağıroğlu,1 Samet Özdemir2 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Bezmialem Vakif University, 2Department of Pharmaceutical Technology, Faculty of Pharmacy, Yeditepe University, Istanbul ...
Burak Celik   +8 more
core   +1 more source

Real‐World Safety of Concomitant Colchicine and Statin Therapy

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan   +5 more
wiley   +1 more source

Binding of Coenzyme B Induces a Major Conformational Change in the Active Site of Methyl-Coenzyme M Reductase

open access: yes, 2016
Methyl-coenzyme M reductase (MCR) is the key enzyme in methane formation by methanogenic Archaea. It converts the thioether methyl-coenzyme M and the thiol coenzyme B into methane and the heterodisulfide of coenzyme M and coenzyme B.
Meike Goenrich (174838)   +4 more
core   +2 more sources

The protective role of coenzyme Q10 and vitamin E on antioxidant defense system in the heart of cadmium treated rats

open access: yes, 2002
Cadmium (Cd) is an important pollutant of environment which accwnulates in the liver and the kidneys, as well as in other tissues. Cd induces oxidative damage causing many metabolic, histological and pathological changes, such as nephrotoxicity ...
Maletić, Snežana   +7 more
core   +1 more source

THE IMPACT OF CARDIOVASCULAR AND BRONCHOPULMONARY DISEASES ON COENZYME Q10 PLASMA CONCENTRATION

open access: yesСеченовский вестник, 2019
Introduction. Coenzyme Q10 plays an important role in the human body. Its main function is not only the transfer of electrons in the mitochondrial respiratory chain for the ATP synthesis, but it is also one of the most powerful antioxidants in the body ...
V. I. Zozina   +4 more
doaj   +1 more source

Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2021
Context: Nanostructured lipid carriers can enhance skin penetration of active substances. Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is overcome by nanostructured lipid carriers.
Ni Luh Dewi Aryani   +4 more
doaj  

Study on the technical requirements of coenzyme Q10 as health food raw materials

open access: yesZhongguo shipin weisheng zazhi, 2023
ObjectiveTo verify the main quality indexes of coenzyme Q10, and study the quality consistency of coenzyme Q10 produced by different processes.MethodsAccording to the Chinese Pharmacopoeia (2020 version) and national food safety standards, the main ...
NING Xiao   +6 more
doaj   +1 more source

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