Results 61 to 70 of about 166,204 (247)
The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy [PDF]
, 2012 This report describes the response of a patient treated with two different coenzyme Q10 extemporaneous pharmaceutical formulations that generated radical changes in her symptoms and life quality.
Lucangioli, Silvia Edith +1 more
core
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Advanced Science, EarlyView.Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source
Antioxidants, 2018 The study aims to examine the effects of coenzyme Q10, (a bioenergetic antioxidant), on the indexes of left ventricular remodeling, oxidative damage, and angiotensin-converting enzyme (ACE) level after acute myocardial infarction (AMI) with left ...
Ram B. Singh +3 more
doaj +1 more source
Coenzyme, cofactor and prosthetic group : ambiguous biochemical jargon [PDF]
, 1994 For enzymes which require non-protein components to be functionally active, it is generally accepted that the term holoenzyme refers to the complete catalytic entity which consists of a protein part known as the apoenzyme and a non-protein constituent ...
Hashim, Onn Haji, Adnan, N.A.
core +1 more source
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
Advanced Science, EarlyView.This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Endocrine RegulationsObjective. Cardiovascular complications are highly prevalent in type 2 diabetes mellitus (T2DM) driven by obesity, dyslipidemia, hypertension, and hypercoagulability associated with insulin resistance.
Kuchmerovska Tamara +5 more
doaj +1 more source
Advanced Science, EarlyView.The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li +9 more
wiley +1 more source
Effects of Coenzyme Q10 on LDL Oxidation In vitro
Acta Medica Iranica, 2013 Coenzyme Q10, a lipid soluble benzoquinone, has excellent antioxidant and membrane stabilizing properties in the cardiac tissue. The present study investigated the effects of coenzyme Q10 on in vitro LDL oxidation quantitavely.
Hiroshi Mabuchi +3 more
doaj +2 more sources
Coenzyme Q10: From Fact to Fiction
, 2015 There is a growing interest in coenzyme Q10 (CoQ10) and its involvement in many aspects of daily living including physical and mental health, energy, aging, stress, skin care and exercise. This book aims to highlight our current understanding of CoQ10 in
Hargreaves, April, Hargreaves, Iain
core +2 more sources
Coenzyme Q4 is a functional substitute for coenzyme Q10 and can be targeted to the mitochondria [PDF]
Coenzyme Q10 ...
Sung, Andrew Y +4 more
core +1 more source