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Cofactor squelching: Artifact or fact?

BioEssays, 2016
Cofactor squelching is the term used to describe competition between transcription factors (TFs) for a limited amount of cofactors in a cell with the functional consequence that TFs in a given cell interfere with the activity of each other. Since cofactor squelching was proposed based primarily on reporter assays some 30 years ago, it has remained ...
S. Schmidt   +3 more
semanticscholar   +4 more sources

Round, round we go - strategies for enzymatic cofactor regeneration.

Natural product reports (Print), 2020
Covering: up to the beginning of 2020Enzymes depending on cofactors are essential in many biosynthetic pathways of natural products. They are often involved in key steps: catalytic conversions that are difficult to achieve purely with synthetic organic ...
Silja Mordhorst, J. Andexer
semanticscholar   +1 more source

Heme Cofactor‐Resembling Fe–N Single Site Embedded Graphene as Nanozymes to Selectively Detect H2O2 with High Sensitivity

Advanced Functional Materials, 2019
Over the past decade, the catalytic activity of nanozymes has been greatly enhanced, but their selectivity is still low and considered a critical issue to overcome. Herein, Fe–N4 single site embedded graphene (Fe–N‐rGO), which resembles the heme cofactor
M. Kim   +9 more
semanticscholar   +1 more source

Cofactor dependent and cofactor independent anticardiolipin antibodies

Thrombosis Research, 1991
Two distinct types of anticardiolipin antibodies are described, one of which requires the presence of a serum factor (cofactor) to bind cardiolipin in ELISA and liposome affinity systems. The second type does not require this cofactor. The requirement of a cofactor for the binding of some but not all anticardiolipin antibodies provides an explanation ...
L W, Chamley, E J, McKay, N S, Pattison
openaire   +2 more sources

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