Results 271 to 280 of about 418,378 (371)

Molybdopterin cofactor from Methanobacterium formicicum formate dehydrogenase

, 1986
Harold D. May, N L Schauer, James G. Ferry   +2 more
openalex   +1 more source

Tau Amyloid Corona‐Shelled Nanoparticle‐Based Drug Screening Platform for Discovering Tau Oligomer‐Degrading Drugs

Aggregate, EarlyView.
Tau amyloid corona‐shelled nanoparticles (TACONs) were synthesized by incubating gold nanoparticles (AuNPs) with tau monomers that had been pre‐reacted with heparin. These TACONs represent a promising high‐throughput screening platform for identifying tau oligomer degraders as potential therapeutic agents for Alzheimer's disease.
Hyo Gi Jung, Dongsung Park, Junho Bang, Yeon Ho Kim, Jae Won Jang, Yonghwan Kim, Hyunji Kim, Seungmin Lee, Wonbin Moon, Kyo Seon Hwang, Jeong Hoon Lee, Dongtak Lee, Dae Sung Yoon   +12 more
wiley   +1 more source

Recent Advances in Elucidating the Mechanism of the NADPH-Cytochrome P450 Reductase-Mediated Electron Transfer Cycle: Experimental and Computational Perspectives. [PDF]

Molecules
Xia S, Hirao H.
europepmc   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Contribution of Second-Shell Residues to PLP-Dependent Transaminase Catalysis: A Case Study of D-Amino Acid Transaminase from <i>Desulfomonile tiedjei</i>. [PDF]

Int J Mol Sci
Bakunova AK, Rudina IV, Popov VO, Bezsudnova EY.   +3 more
europepmc   +1 more source

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

The influence of protein electrostatics on potential inversion in flavoproteins. [PDF]

Chem Sci
Singh N, Zhang P, Beratan DN.
europepmc   +1 more source

Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor

Science, 2011
T. Spatzal, Müge Aksoyoglu, Limei Zhang, S. Andrade, E. Schleicher, S. Weber, D. Rees, O. Einsle   +7 more
semanticscholar   +1 more source

Advances in miRNA research: Unraveling the complexities of gene regulation

Animal Models and Experimental Medicine, EarlyView.
Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley   +1 more source

Structural basis of SIRT2 pre-catalysis NAD⁺ binding dynamics and mechanism. [PDF]

RSC Chem Biol
Zhang N, Pow KC, Chen L, Hao Q.
europepmc   +1 more source