Results 111 to 120 of about 2,155 (232)
Dynamic Molecular Cocrystals with Alkyl Chain Dependent Thermosalient Phase Transitions
Advanced Science, Volume 12, Issue 26, July 10, 2025.A series of cocrystals containing 5‐fluorocytosine and fatty acids with varying alkyl chain lengths are synthesized, demonstrating a systematic modulation of thermosalient phase transition temperatures across a broad range (≈100 K). This study reveals a linear correlation between interlayer hydrophobic interactions and transition temperatures, offering
Jiantao Meng +4 more
wiley +1 more source
Two-component organic crystals without hydrogen bonding: structure and intermolecular interactions in bimolecular stacking [PDF]
, 2017 A survey of crystal structures including two organic compounds unable to form hydrogen bonding has been carried out using the Cambridge Structural Database. Such systems are common and numerous.
A. Gavezzotti, L. Lo Presti, V. Colombo
core +1 more source
Chemistry – A European Journal, Volume 31, Issue 33, June 12, 2025.Pamoic acid:quinoline cocrystal and pamoate:quinolinium salts can be synthetized by mechanochemistry tuning the reaction conditions. Computational analysis of the crystal packing reveals the main factors driving the formation of either forms. This approach and subsequent rationalization pave the way to the synthesis of pharmaceutically active ...
Andrea Daolio +5 more
wiley +1 more source
Molecules, 2019 Four novel xanthohumol (XN) cocrystals with pharmaceutically acceptable coformers, such as nicotinamide (NIC), glutarimide (GA), acetamide (AC), and caffeine (CF) in the 1:1 stoichiometry were obtained by the slow evaporation solution growth technique ...
Iwona Budziak +2 more
doaj +1 more source
Crystals, 2020 Tuning and controlling the solid-state photophysical properties of organic luminophore are very important to develop next-generation organic luminescent materials.
Torvid Feiler +5 more
doaj +1 more source
IUCrJIn the search for new active pharmaceutical ingredients, the precise control of the chemistry of cocrystals becomes essential. One crucial step within this chemistry is proton migration between cocrystal coformers to form a salt, usually anticipated by ...
Ewa Patyk-Kaźmierczak +6 more
doaj +1 more source
A REVIEW ON ADVANCES IN PHARMACEUTICAL CO-CRYSTAL PREPARATION ROUTES, INTELLECTUAL PROPERTY PERSPECTIVE AND REGULATORY ASPECTS [PDF]
, 2022 As in recent years, due to the pervasiveness of poorly soluble APIs that demonstrates poor and erratic bioavailability, pharmaceutical cocrystal’s applicability to tailor the physicochemical properties has gained attention.
BURADE, KISHOR KUMAR B. +4 more
core +1 more source
Searching for Suitable Kojic Acid Coformers: From Cocrystals and Salt to Eutectics
, 2023 Renren Sun +4 more
openalex +1 more source
Pharmaceutical Development and Technology, 2018 This study explores the preparation and investigation of dissolution properties of piroxicam cocrystals. Differential scanning calorimetry (DSC) was used to determine the capability of resorcinol (RES), methylparaben (MPB), and vanillin (VAN) to form cocrystals with piroxicam (PRX). Generation of cocrystals was attempted by liquid assisted grinding and
Shahram, Emami +3 more
openaire +2 more sources
FORMULATION AND EVALUATION OF COCRYSTALS OF A BCS CLASS II DRUG USING GLYCINE AS COFORMER [PDF]
, 2022 Objective: Development of pharmaceutical co-crystals is an interesting area of research as co-crystals are unique because they have the advantages of maintaining drug’s intrinsic properties along with improvement in its physicochemical attributes ...
ANAND, RACHNA, NANDA, ARUN
core +1 more source