The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders [PDF]
Understanding the neurochemical basis for cognitive function is one of the major goals of neuroscience, with a potential impact on the diagnosis, prevention and treatment of a range of psychiatric and neurological disorders.
Akagbosu+172 more
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AbstractThe term vascular cognitive disorder (VCD) refers to a heterogeneous group of disorders in which the primary feature is cognitive impairment attributable to cerebrovascular disease (CVD). This includes not only vascular dementia (VaD) but also cognitive impairment of insufficient severity to meet diagnostic criteria for dementia.
Paradise, Matt, Sachdev, PS
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Acetylcholine neuromodulation in normal and abnormal learning and memory: vigilance control in waking, sleep, autism, amnesia, and Alzheimer's disease [PDF]
This article provides a unified mechanistic neural explanation of how learning, recognition, and cognition break down during Alzheimer's disease, medial temporal amnesia, and autism.
Grossberg, Stephen
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Effect of neurostimulation on cognition and mood in refractory epilepsy. [PDF]
Epilepsy is a common, debilitating neurological disorder characterized by recurrent seizures. Mood disorders and cognitive deficits are common comorbidities in epilepsy that, like seizures, profoundly influence quality of life and can be difficult to ...
Chan, Alvin Y+3 more
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Alexithymia and apathy in Parkinson's disease: neurocognitive correlates [PDF]
Non-motor symptoms such as neuropsychiatric and cognitive dysfunction have been found to be common in Parkinson’s disease (PD) but the relation between such symptoms is poorly understood.
Bogdanova, Yelena, Cronin-Golomb, A.
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The effects of context processing on social cognition impairments in adults with Aspergers syndrome [PDF]
Social cognition—the basis of all communicative and otherwise interpersonal relationships—is embedded in specific contextual circumstances which shape intrinsic meanings.
Báez Buitrago, Sandra Jimena+1 more
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Enactivism, other minds, and mental disorders [PDF]
Although enactive approaches to cognition vary in terms of their character and scope, all endorse several core claims. The first is that cognition is tied to action.
Krueger, Joel
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Social cognition and Theory of Mind: controversies and promises for understanding major psychiatric disorders [PDF]
The term social cognition generally refers to the mental operations that underlie social interactions including the perception and interpretation of the intentions, dispositions, and behaviors of others and the generation of a response to these behaviors.
Brietzke, Elisa+3 more
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Genetics of recessive cognitive disorders [PDF]
Most severe forms of intellectual disability (ID) have specific genetic causes. Numerous X chromosome gene defects and disease-causing copy-number variants have been linked to ID and related disorders, and recent studies have revealed that sporadic cases are often due to dominant de novo mutations with low recurrence risk.
Luciana Musante, H. Hilger Ropers
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A P300-based cognitive assessment battery [PDF]
© 2015 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.Background: It is well established that some patients who are diagnosed as being in a vegetative state or a minimally conscious state show reliable signs of volition that may only
Andrews+41 more
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