Results 61 to 70 of about 3,471,103 (309)

Conscious cognitive effort in cognitive control

open access: yesWIREs Cognitive Science, 2022
Cognitive effort is thought to be familiar in everyday life, ubiquitous across multiple variations of task and circumstance, and integral to cost/benefit computations that are themselves central to the proper functioning of cognitive control. In particular, cognitive effort is thought to be closely related to the assessment of cognitive control’s costs.
openaire   +3 more sources

Design activities: how to analyze cognitive effort associated to cognitive treatments? [PDF]

open access: yes, 2003
Working memory issues are important in many real activities. Thus, measuring cognitive effort (or mental load) has been a main research topic for years in cognitive ergonomics, though no consensual method to study such aspect has been proposed.
Bonnardel, N, Piolat, A
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Using video game telemetry data to research motor chunking, action latencies, and complex cognitive-motor skill learning

open access: yes, 2017
Many theories of complex cognitive‐motor skill learning are built on the notion that basic cognitive processes group actions into easy‐to‐perform sequences. The present work examines predictions derived from laboratory‐based studies of motor chunking and

core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Application of a Blended Learning Model in Agricultural Vocational High Schools

open access: yesJurnal Pendidikan Teknologi dan Kejuruan, 2017
Based on case studies that have been conducted in SMK Pertanian Pembangunan Negeri Lembang, waste treatment subjects still used a conventional method, and the students were less enthusiastic in the learning process.
Sari Nurmayani   +2 more
doaj   +1 more source

A general framework for reinforcement learning in cognitive architectures

open access: yes
Recent advancements in reinforcement learning (RL), particularly deep RL, show the capacity of this paradigm to perform varied and complex tasks. However, a series of exploration, generalization, and adaptation challenges hold RL back from operating in ...
Gudwin, Ricardo   +5 more
core   +1 more source

SCRIPTKELL : a tool for measuring cognitive effort and time processing in writing and other complex cognitive activities [PDF]

open access: yes, 1999
We present SCRIPTKELL, a computer-assisted experimental tool that makes it possible to measure the time and cognitive effort allocated to the subprocesses of writing and other cognitive activities, SCRIPTKELL was designed to easily use and modulate ...
Roussey, JY   +4 more
core  

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