Results 61 to 70 of about 1,584,313 (260)

Distinct neuropsychological correlates of cognitive, behavioural and affective apathy sub-domains in acquired brain injury.

open access: yesFrontiers in Neurology, 2014
Apathy has a high prevalence and a significant contribution to treatment and rehabilitation outcomes in acquired brain damage. Research on the disorder’s neuropsychological correlates has produced mixed results.
Progress eNjomboro, Shoumitro eDeb
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Effect of boxing exergame addition on brain-derived neurotrophic factor of elderly women [PDF]

open access: yesRomanian Journal of Neurology
Background and objectives. The elderly population is growing rapidly. The aging process will result in the decline of cognitive functions. The frequency of cognitive impairment is higher in women than in men, resulting in a greater risk of decreased ...
Nadia Rizki Rahmawati   +3 more
doaj   +1 more source

Cognitive Metaphysics [PDF]

open access: yesFrontiers in Psychology, 2018
In recent years philosophers have been interested in the methodology of metaphysics. Most of these developments are related to formal work in logic or physics, often against the backdrop of the Carnap-Quine debate on ontology. Drawing on Quine's later work, I argue that a psychological or cognitive perspective on metaphysical topics may be a valuable ...
openaire   +4 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Long-Term Cognitive Outcomes of Esketamine Nasal Spray in Treatment-Resistant Depression: A Preliminary Report

open access: yesPharmaceuticals
Background/Objectives: Ketamine/esketamine has a rapid/robust antidepressant effect on treatment-resistant depression (TRD). However, its long-term cognitive effects remain unclear.
Matildes de Freitas Menezes Sobreiro   +8 more
doaj   +1 more source

Gray Matter Volume and Cognitive Performance During Normal Aging. A Voxel-Based Morphometry Study

open access: yesFrontiers in Aging Neuroscience, 2018
Normal aging is characterized by decline in cognitive functioning in conjunction with extensive gray matter (GM) atrophy. A first aim of this study was to determine GM volume differences related to aging by comparing two groups of participants, middle ...
Stephen Ramanoël   +10 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Cognitive, linguistic, and methodological considerations in teaching professional vocabulary to information technology (IT) students.

open access: yesВикладання мов у вищих навчальних закладах освіти на сучасному етапі: Міжпредметні зв'язки
The article examines modern facets of English language teaching to IT students in Ukraine. A mixed-methods approach was taken for the research: a review of modern approaches to teaching professional vocabulary to IT students; assessment of the ...
V. Borshchovetska   +3 more
doaj   +1 more source

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